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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Fzd8 (Mus musculus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0001934 positive regulation of protein phosphorylation IMP GO:0001944 vasculature development IBA GO:0006357 regulation of transcription from RNA polymerase II promoter IBA GO:0007165 signal transduction IPI GO:0007166 cell surface receptor linked signaling pathway IEA GO:0007186 G-protein coupled receptor protein signaling pathway IEA GO:0007275 multicellular organismal development IEA GO:0007409 axonogenesis IBA GO:0007420 brain development IBA GO:0008406 gonad development IBA GO:0009790 embryo development IBA GO:0016055 Wnt receptor signaling pathway IEA GO:0033077 T cell differentiation in thymus IMP GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0060070 canonical Wnt receptor signaling pathway IDA GO:0060070 canonical Wnt receptor signaling pathway IGI GO:0060070 canonical Wnt receptor signaling pathway IMP cellular_component GO:0005737 cytoplasm IBA GO:0005794 Golgi apparatus IEA GO:0005886 plasma membrane IDA GO:0016020 membrane IEA GO:0016021 integral to membrane IEA GO:0042995 cell projection IBA molecular_function GO:0004871 signal transducer activity IEA GO:0004872 receptor activity IEA GO:0004888 transmembrane signaling receptor activity IEA GO:0004930 G-protein coupled receptor activity IEA GO:0005102 receptor binding IPI GO:0005515 protein binding IPI GO:0017147 Wnt-protein binding IPI GO:0030165 PDZ domain binding IBA GO:0030165 PDZ domain binding IPI GO:0030165 PDZ domain binding ISO GO:0042813 Wnt-activated receptor activity IPI

Protein-protein interaction details for Fzd8 (Mus musculus) (Information is obtained from BioGRID)

Interacting mouse protein Experiment Type PubMed ID Gopc Two-hybrid physical 11520064 Gopc Affinity Capture-Western physical 11520064 Gopc Reconstituted Complex physical 11520064 Wnt1 Affinity Capture-Western physical 15454084 Ryk Affinity Capture-Western physical 15454084 Wnt1 Phenotypic Suppression genetic 15143170