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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Grb10 (Mus musculus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0007165 signal transduction TAS GO:0008286 insulin receptor signaling pathway ISO GO:0030178 negative regulation of Wnt receptor signaling pathway IDA GO:0030178 negative regulation of Wnt receptor signaling pathway ISO GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway ISO GO:0032868 response to insulin stimulus ISO GO:0042326 negative regulation of phosphorylation IDA GO:0042327 positive regulation of phosphorylation ISO GO:0045719 negative regulation of glycogen biosynthetic process ISO GO:0045719 negative regulation of glycogen biosynthetic process TAS GO:0046325 negative regulation of glucose import IMP GO:0046627 negative regulation of insulin receptor signaling pathway IMP GO:0048009 insulin-like growth factor receptor signaling pathway IPI cellular_component GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS molecular_function GO:0001784 phosphotyrosine binding TAS GO:0004872 receptor activity IEA GO:0005070 SH3/SH2 adaptor activity IPI GO:0005158 insulin receptor binding IPI GO:0005158 insulin receptor binding ISO GO:0005515 protein binding IPI

Protein-protein interaction details for Grb10 (Mus musculus) (Information is obtained from BioGRID)

Interacting mouse protein Experiment Type PubMed ID Nedd4 Two-hybrid physical 10446181 Nedd4 Affinity Capture-Western physical 10446181 Nedd4 Reconstituted Complex physical 20980250 Nedd4 Co-crystal Structure physical 20980250 Igf1r Co-crystal Structure physical 20980250