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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Grb2 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0007265Ras protein signal transductionTAS
GO:0007568agingISO
GO:0008286insulin receptor signaling pathwayISO
GO:0008543fibroblast growth factor receptor signaling pathwayIGI
GO:0030154cell differentiationIMP
GO:0031623receptor internalizationISO
GO:0042770signal transduction in response to DNA damageISO
GO:0043408regulation of MAPKKK cascadeIGI
GO:0048646anatomical structure formation involved in morphogenesisIMP
GO:0051291protein heterooligomerizationISO
GO:0060670branching involved in embryonic placenta morphogenesisIMP
GO:0071479cellular response to ionizing radiationISO
GO:2000379positive regulation of reactive oxygen species metabolic processISO
cellular_component
GO:0005737cytoplasmIDA
GO:0005794Golgi apparatusIEA
GO:0012506vesicle membraneIDA
GO:0016020membraneIDA
GO:0043234protein complexISO
molecular_function
GO:0001784phosphotyrosine bindingISO
GO:0004872receptor activityIEA
GO:0005070SH3/SH2 adaptor activityIDA
GO:0005154epidermal growth factor receptor bindingISO
GO:0005515protein bindingIPI
GO:0019904protein domain specific bindingIPI
GO:0019904protein domain specific bindingISO
GO:0043560insulin receptor substrate bindingISO
GO:0046875ephrin receptor bindingISO
GO:0051219phosphoprotein bindingISO

Protein-protein interaction details for Grb2 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
CblAffinity Capture-Westernphysical9174058
Pik3r1Affinity Capture-Westernphysical9174058
Pik3r1Reconstituted Complexphysical9174058
TekTwo-hybridphysical10521483
TekReconstituted Complexphysical10521483
TekAffinity Capture-Westernphysical10521483
MetReconstituted Complexphysical17449471
Dvl2Affinity Capture-Westernphysical19920076
CblAffinity Capture-Westernphysical17372273
EgfrAffinity Capture-Westernphysical17372273