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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TICAM1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002224 toll-like receptor signaling pathway TAS GO:0002281 macrophage activation involved in immune response IEA GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006915 apoptosis IEA GO:0006954 inflammatory response IEA GO:0007165 signal transduction IMP GO:0007249 I-kappaB kinase/NF-kappaB cascade TAS GO:0008063 Toll signaling pathway TAS GO:0008624 induction of apoptosis by extracellular signals IEA GO:0030890 positive regulation of B cell proliferation IEA GO:0031398 positive regulation of protein ubiquitination IEA GO:0031663 lipopolysaccharide-mediated signaling pathway IEA GO:0032092 positive regulation of protein binding IEA GO:0032481 positive regulation of type I interferon production IEA GO:0032496 response to lipopolysaccharide IEA GO:0032755 positive regulation of interleukin-6 production IEA GO:0032760 positive regulation of tumor necrosis factor production IEA GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IMP GO:0043330 response to exogenous dsRNA IEA GO:0043496 regulation of protein homodimerization activity IEA GO:0045080 positive regulation of chemokine biosynthetic process IEA GO:0045087 innate immune response TAS GO:0045359 positive regulation of interferon-beta biosynthetic process IEA GO:0045429 positive regulation of nitric oxide biosynthetic process IEA GO:0051092 positive regulation of NF-kappaB transcription factor activity IEA GO:0051607 defense response to virus IEA cellular_component GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS GO:0010008 endosome membrane TAS molecular_function GO:0004871 signal transducer activity IMP GO:0005515 protein binding IPI GO:0019901 protein kinase binding IPI

Protein-protein interaction details for TICAM1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID RIPK1 Affinity Capture-Western physical 15064760 RIPK1 Affinity Capture-Western physical 15064760 RIPK3 Affinity Capture-Western physical 15064760 RNF216 Affinity Capture-Western physical 16968706 RIPK1 Affinity Capture-Western physical 19734906 TRAF2 Two-hybrid physical 20047764 TRAF6 Two-hybrid physical 20047764 TRAF2 Affinity Capture-Western physical 20047764 TRAF6 Affinity Capture-Western physical 20047764 UBC Affinity Capture-Western physical 20047764 TRAF2 Biochemical Activity physical 20047764 TANK Affinity Capture-MS physical 21903422 TBK1 Affinity Capture-MS physical 21903422