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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CTBP1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP GO:0006468 protein phosphorylation TAS GO:0008285 negative regulation of cell proliferation TAS GO:0019079 viral genome replication TAS GO:0030154 cell differentiation IEA GO:0031065 positive regulation of histone deacetylation IMP GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor IMP GO:0034401 regulation of transcription by chromatin organization IMP GO:0035067 negative regulation of histone acetylation IMP GO:0044419 interspecies interaction between organisms IEA GO:0045892 negative regulation of transcription, DNA-dependent ISS GO:0050872 white fat cell differentiation ISS GO:0051726 regulation of cell cycle IMP GO:0055114 oxidation-reduction process IEA GO:0090241 negative regulation of histone H4 acetylation IMP cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus ISS GO:0005667 transcription factor complex IEA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IEA GO:0017053 transcriptional repressor complex ISS molecular_function GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0005488 binding IEA GO:0005515 protein binding IPI GO:0008022 protein C-terminus binding TAS GO:0008134 transcription factor binding IPI GO:0016491 oxidoreductase activity IEA GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA GO:0019904 protein domain specific binding IPI GO:0048037 cofactor binding IEA GO:0051287 NAD binding IEA GO:0051287 NAD binding ISS

Protein-protein interaction details for CTBP1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PNN Reconstituted Complex physical 15542832 PNN Affinity Capture-Western physical 15542832 IKZF1 Reconstituted Complex physical 10766745 IKZF1 Affinity Capture-Western physical 10766745 SMAD6 Affinity Capture-Western physical 14645520 RBBP8 Reconstituted Complex physical 10196224 RBBP8 Affinity Capture-Western physical 10196224 TGIF1 Affinity Capture-Western physical 10995736 NRIP1 Reconstituted Complex physical 15060175 MDM2 Far Western physical 12867035 MDM2 Affinity Capture-Western physical 12867035 HDAC1 Reconstituted Complex physical 11022042 HDAC3 Reconstituted Complex physical 11022042 HDAC4 Reconstituted Complex physical 11022042 HDAC5 Reconstituted Complex physical 11022042 HDAC9 Reconstituted Complex physical 11022042 BRCA1 Affinity Capture-Western physical 10196224 HDAC1 Affinity Capture-Western physical 10995736 TGIF1 Two-hybrid physical 10995736 HDAC2 Affinity Capture-Western physical 10766745 KAT2B Biochemical Activity physical 9824164 SIP1 Affinity Capture-Western physical 12714599 TBP Reconstituted Complex physical 11959865 GTF2B Reconstituted Complex physical 11959865 FOXP1 Affinity Capture-Western physical 14701752 FOXP2 Affinity Capture-Western physical 14701752 FOXP2 Two-hybrid physical 14701752 MLL Reconstituted Complex physical 12829790 MLL Affinity Capture-Western physical 12829790 CBX4 Reconstituted Complex physical 12829790 CBX4 Biochemical Activity physical 12679040 HDAC1 Reconstituted Complex physical 9650586 MECOM Affinity Capture-Western physical 11568182 MECOM Phenotypic Enhancement genetic 11568182 MECOM Phenotypic Suppression genetic 11568182 CBX4 Affinity Capture-Western physical 11583618 IKZF4 Two-hybrid physical 12444977 IKZF4 Affinity Capture-Western physical 12444977 CBX4 Two-hybrid physical 9858600 CTBP2 Two-hybrid physical 9858600 MECOM Affinity Capture-Western physical 11313276 MECOM Reconstituted Complex physical 11313276 ZEB1 Affinity Capture-Western physical 10359772 RBBP8 Two-hybrid physical 9535825 RBBP8 Reconstituted Complex physical 9535825 RBBP8 Reconstituted Complex physical 9535825 RBBP8 Affinity Capture-Western physical 9535825 RBBP8 Affinity Capture-Western physical 9535825 ACTL6B Phenotypic Enhancement genetic 12565893 ACTL6B Affinity Capture-Western physical 12565893 ACTL6B Two-hybrid physical 12565893 HTT Affinity Capture-Western physical 11739372 TBL1X Affinity Capture-Western physical 18374649 NRIP1 Affinity Capture-Western physical 18374649 ZNF217 Affinity Capture-MS physical 19242095 RCOR1 Affinity Capture-MS physical 19242095 SATB1 Reconstituted Complex physical 19103759 SATB1 Affinity Capture-Western physical 19103759 SATB1 Affinity Capture-Western physical 19103759 HIC1 Affinity Capture-Western physical 17213307 HIC1 Affinity Capture-Western physical 17213307 ZNF217 Affinity Capture-Western physical 17130829 CTBP1 Affinity Capture-Western physical 19754958 TCF4 Two-hybrid physical 20211142 LCOR Two-hybrid physical 20211142 TP53 Affinity Capture-Western physical 18765668 HDAC1 Affinity Capture-Western physical 18765668 TP53 Affinity Capture-Western physical 18765668 HIC1 Two-hybrid physical 19486893 HGD Affinity Capture-Western physical 16787403 EHMT2 Affinity Capture-Western physical 16702210 EHMT1 Affinity Capture-Western physical 16702210 WIZ Affinity Capture-Western physical 16702210 ZNF217 Affinity Capture-Western physical 18625718 APC Affinity Capture-Western physical 16510875 PLK1 Affinity Capture-Western physical 16481748 TUBG1 Affinity Capture-Western physical 16481748 HSD11B2 Affinity Capture-Western physical 12878208 TCF7L2 Reconstituted Complex physical 12711682 LCOR Reconstituted Complex physical 12535528 LCOR Affinity Capture-Western physical 12535528 KDM1A Affinity Capture-MS physical 16140033 CREBBP Affinity Capture-Western physical 16122695 EP300 Affinity Capture-Western physical 16122695 KAT2B Affinity Capture-Western physical 16122695 KAT2A Affinity Capture-Western physical 16122695 HSD11B2 Affinity Capture-Western physical 12082639 KDM1A Affinity Capture-MS physical 16079794 SP1 Affinity Capture-Western physical 16036112 SP1 Affinity Capture-Western physical 16036112 HDAC2 Affinity Capture-Western physical 16036112 EP300 Reconstituted Complex physical 15834423 CREBBP Reconstituted Complex physical 15834423 KAT2B Reconstituted Complex physical 15834423 EP300 Affinity Capture-Western physical 15834423 EP300 Reconstituted Complex physical 15834423 ZEB1 Affinity Capture-Western physical 17967884 RREB1 Affinity Capture-Western physical 17967884 EHMT2 Affinity Capture-Western physical 17967884 WIZ Affinity Capture-Western physical 17967884 RCOR1 Affinity Capture-Western physical 17967884 HDAC2 Affinity Capture-Western physical 17967884 KDM1A Affinity Capture-Western physical 17967884 CDYL Affinity Capture-Western physical 17967884 ZNF217 Affinity Capture-Western physical 17967884 UBE2I Affinity Capture-Western physical 17967884 RCOR1 Reconstituted Complex physical 17967884 HDAC2 Reconstituted Complex physical 17967884 KDM1A Reconstituted Complex physical 17967884 ZNF217 Affinity Capture-Western physical 17967884 BCORL1 Affinity Capture-Western physical 17379597 BCORL1 Affinity Capture-Western physical 17379597 BCORL1 Co-localization physical 17379597 SERPINH1 Affinity Capture-Western physical 17546044 BCL3 Affinity Capture-MS physical 20547759 BCL3 Affinity Capture-Western physical 20547759 KDM1A Affinity Capture-Western physical 20547759 AKT1 Affinity Capture-Western physical 20361981 CBX4 Affinity Capture-Western physical 20361981 CTBP1 Affinity Capture-Western physical 20361981 TGIF1 Affinity Capture-Western physical 20361981 HDAC9 Affinity Capture-Western physical 20361981 UBC Affinity Capture-Western physical 20361981 HIST3H3 Biochemical Activity physical 12700765 EHMT1 Co-localization physical 12700765 SPEN Affinity Capture-Western physical 16287852 SPEN Reconstituted Complex physical 16287852 RBBP8 Reconstituted Complex physical 16287852 ZBP1 Affinity Capture-MS physical 21903422 ZBP1 Reconstituted Complex physical 21903422 SOBP Two-hybrid physical 21900206 IKZF1 Two-hybrid physical 21900206 ZNF219 Two-hybrid physical 21900206 LCORL Two-hybrid physical 21900206 CHD3 Two-hybrid physical 21900206 RBBP5 Two-hybrid physical 21900206 CTNNA1 Two-hybrid physical 21900206 ZEB1 Two-hybrid physical 10567582 ZEB1 Reconstituted Complex physical 10567582