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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Ptpn6 (
Mus musculus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0002924
negative regulation of humoral immune response mediated by circulating immunoglobulin
IMP
GO:0006470
protein dephosphorylation
IDA
GO:0006470
protein dephosphorylation
IMP
GO:0008284
positive regulation of cell proliferation
ISO
GO:0014068
positive regulation of phosphatidylinositol 3-kinase cascade
ISO
GO:0016311
dephosphorylation
IEA
GO:0019221
cytokine-mediated signaling pathway
TAS
GO:0035556
intracellular signal transduction
IDA
GO:0042130
negative regulation of T cell proliferation
IMP
GO:0042267
natural killer cell mediated cytotoxicity
IMP
GO:0043407
negative regulation of MAP kinase activity
IMP
GO:0043409
negative regulation of MAPKKK cascade
IMP
GO:0045577
regulation of B cell differentiation
IMP
GO:0050732
negative regulation of peptidyl-tyrosine phosphorylation
IMP
GO:0050732
negative regulation of peptidyl-tyrosine phosphorylation
ISO
GO:0050853
B cell receptor signaling pathway
IMP
GO:0050860
negative regulation of T cell receptor signaling pathway
IMP
GO:2000045
regulation of G1/S transition of mitotic cell cycle
ISO
cellular_component
GO:0005634
nucleus
ISO
GO:0005737
cytoplasm
ISO
GO:0005737
cytoplasm
TAS
GO:0042105
alpha-beta T cell receptor complex
IDA
molecular_function
GO:0001784
phosphotyrosine binding
IPI
GO:0004721
phosphoprotein phosphatase activity
IEA
GO:0004725
protein tyrosine phosphatase activity
IDA
GO:0005515
protein binding
IPI
GO:0016787
hydrolase activity
IEA
GO:0016791
phosphatase activity
IEA
GO:0017124
SH3 domain binding
IDA
GO:0042169
SH2 domain binding
IDA
GO:0046703
natural killer cell lectin-like receptor binding
ISO
Protein-protein interaction details for Ptpn6 (
Mus musculus
)
(Information is obtained from BioGRID)
Interacting mouse protein
Experiment
Type
PubMed ID
Ncoa3
Two-hybrid
physical
11668176