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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Ptpn6 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002924negative regulation of humoral immune response mediated by circulating immunoglobulinIMP
GO:0006470protein dephosphorylationIDA
GO:0006470protein dephosphorylationIMP
GO:0008284positive regulation of cell proliferationISO
GO:0014068positive regulation of phosphatidylinositol 3-kinase cascadeISO
GO:0016311dephosphorylationIEA
GO:0019221cytokine-mediated signaling pathwayTAS
GO:0035556intracellular signal transductionIDA
GO:0042130negative regulation of T cell proliferationIMP
GO:0042267natural killer cell mediated cytotoxicityIMP
GO:0043407negative regulation of MAP kinase activityIMP
GO:0043409negative regulation of MAPKKK cascadeIMP
GO:0045577regulation of B cell differentiationIMP
GO:0050732negative regulation of peptidyl-tyrosine phosphorylationIMP
GO:0050732negative regulation of peptidyl-tyrosine phosphorylationISO
GO:0050853B cell receptor signaling pathwayIMP
GO:0050860negative regulation of T cell receptor signaling pathwayIMP
GO:2000045regulation of G1/S transition of mitotic cell cycleISO
cellular_component
GO:0005634nucleusISO
GO:0005737cytoplasmISO
GO:0005737cytoplasmTAS
GO:0042105alpha-beta T cell receptor complexIDA
molecular_function
GO:0001784phosphotyrosine bindingIPI
GO:0004721phosphoprotein phosphatase activityIEA
GO:0004725protein tyrosine phosphatase activityIDA
GO:0005515protein bindingIPI
GO:0016787hydrolase activityIEA
GO:0016791phosphatase activityIEA
GO:0017124SH3 domain bindingIDA
GO:0042169SH2 domain bindingIDA
GO:0046703natural killer cell lectin-like receptor bindingISO

Protein-protein interaction details for Ptpn6 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Ncoa3Two-hybridphysical11668176