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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Hdac2 (
Mus musculus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
IGI
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
ISO
GO:0006344
maintenance of chromatin silencing
ISO
GO:0006351
transcription, DNA-dependent
IEA
GO:0006355
regulation of transcription, DNA-dependent
IEA
GO:0006476
protein deacetylation
IDA
GO:0008284
positive regulation of cell proliferation
IGI
GO:0008284
positive regulation of cell proliferation
ISO
GO:0009913
epidermal cell differentiation
IGI
GO:0010870
positive regulation of receptor biosynthetic process
ISO
GO:0010977
negative regulation of neuron projection development
IDA
GO:0010977
negative regulation of neuron projection development
ISO
GO:0016358
dendrite development
IMP
GO:0016568
chromatin modification
TAS
GO:0016575
histone deacetylation
IGI
GO:0016575
histone deacetylation
ISO
GO:0021766
hippocampus development
IGI
GO:0030182
neuron differentiation
IGI
GO:0042475
odontogenesis of dentine-containing tooth
IGI
GO:0042733
embryonic digit morphogenesis
IGI
GO:0043066
negative regulation of apoptosis
IGI
GO:0043433
negative regulation of sequence-specific DNA binding transcription factor activity
ISO
GO:0045862
positive regulation of proteolysis
ISO
GO:0045892
negative regulation of transcription, DNA-dependent
IDA
GO:0045892
negative regulation of transcription, DNA-dependent
ISO
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISO
GO:0048714
positive regulation of oligodendrocyte differentiation
IGI
GO:0060789
hair follicle placode formation
IGI
GO:0061029
eyelid development in camera-type eye
IGI
GO:0061198
fungiform papilla formation
IGI
GO:0090090
negative regulation of canonical Wnt receptor signaling pathway
IGI
cellular_component
GO:0000118
histone deacetylase complex
TAS
GO:0000785
chromatin
ISO
GO:0000790
nuclear chromatin
IDA
GO:0000792
heterochromatin
IDA
GO:0005634
nucleus
ISO
GO:0005657
replication fork
IDA
GO:0005667
transcription factor complex
IPI
GO:0005737
cytoplasm
TAS
GO:0016580
Sin3 complex
ISO
GO:0016581
NuRD complex
ISO
GO:0017053
transcriptional repressor complex
IPI
GO:0035098
ESC/E(Z) complex
ISO
molecular_function
GO:0003682
chromatin binding
IDA
GO:0003700
sequence-specific DNA binding transcription factor activity
IDA
GO:0004407
histone deacetylase activity
IDA
GO:0004407
histone deacetylase activity
ISO
GO:0004407
histone deacetylase activity
TAS
GO:0005515
protein binding
IPI
GO:0008134
transcription factor binding
ISO
GO:0008134
transcription factor binding
TAS
GO:0016787
hydrolase activity
IEA
GO:0019899
enzyme binding
IPI
GO:0019899
enzyme binding
ISO
GO:0031072
heat shock protein binding
ISO
GO:0031078
histone deacetylase activity (H3-K14 specific)
IEA
GO:0032041
NAD-dependent histone deacetylase activity (H3-K14 specific)
IEA
GO:0032129
histone deacetylase activity (H3-K9 specific)
IEA
GO:0033558
protein deacetylase activity
IDA
GO:0033558
protein deacetylase activity
ISO
GO:0034739
histone deacetylase activity (H3-K16 specific)
IEA
GO:0043565
sequence-specific DNA binding
ISO
GO:0046969
NAD-dependent histone deacetylase activity (H3-K9 specific)
IEA
GO:0046970
NAD-dependent histone deacetylase activity (H4-K16 specific)
IEA
Protein-protein interaction details for Hdac2 (
Mus musculus
)
(Information is obtained from BioGRID)
Interacting mouse protein
Experiment
Type
PubMed ID
Ikzf1
Co-fractionation
physical
10204490
Sall1
Reconstituted Complex
physical
11836251
Yy1
Affinity Capture-Western
physical
17220375
Zfpm1
Affinity Capture-MS
physical
19654328
Ctbp1
Two-hybrid
physical
20211142
Hdac9
Two-hybrid
physical
20211142
Tcf7l2
Affinity Capture-Western
physical
19503085
Pou5f1
Affinity Capture-MS
physical
20362541
Sall4
Affinity Capture-MS
physical
20362541
Tcfcp2l1
Affinity Capture-MS
physical
20362541
Esrrb
Affinity Capture-MS
physical
20362541
Nanog
Affinity Capture-MS
physical
17093407
Pou5f1
Affinity Capture-MS
physical
17093407
Nanog
Affinity Capture-MS
physical
18454139
Nanog
Affinity Capture-Western
physical
18454139
Nanog
Affinity Capture-Western
physical
18454139
Pou5f1
Affinity Capture-Western
physical
18454139
Sin3a
Affinity Capture-Western
physical
18454139
Mta1
Affinity Capture-Western
physical
18454139
Mta2
Affinity Capture-Western
physical
18454139
Mbd3
Affinity Capture-Western
physical
18454139
Rbbp7
Affinity Capture-Western
physical
18454139
Pou5f1
Affinity Capture-Western
physical
18454139
Mta1
Affinity Capture-Western
physical
18454139
Mta2
Affinity Capture-Western
physical
18454139
Sin3a
Affinity Capture-Western
physical
16109738
Sp3
Affinity Capture-Western
physical
16109738
Hdac1
Affinity Capture-Western
physical
16109738
Sin3a
Affinity Capture-Western
physical
16109738
Sp3
Affinity Capture-Western
physical
16109738
Pml
Affinity Capture-Western
physical
18454139
Gata1
Affinity Capture-Western
physical
15920471
Mta2
Affinity Capture-Western
physical
15920471
Irs1
Affinity Capture-Western
physical
15522123
Pdx1
Affinity Capture-Western
physical
15496408
Pdx1
Affinity Capture-Western
physical
15496408
Pdx1
Reconstituted Complex
physical
15496408
Pdx1
Reconstituted Complex
physical
15496408
Cry1
Reconstituted Complex
physical
15226430
Cry1
Affinity Capture-Western
physical
15226430
Rnf2
Affinity Capture-MS
physical
17296600
Arid1a
Affinity Capture-Western
physical
17255939
Fosb
Affinity Capture-Western
physical
21258411
Gfi1b
Reconstituted Complex
physical
17707228
Ddx20
Reconstituted Complex
physical
12007404