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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ADRB1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001996positive regulation of heart rate by epinephrine-norepinephrineIEA
GO:0002025vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressureIEA
GO:0003061positive regulation of the force of heart contraction by norepinephrineIEA
GO:0003084positive regulation of systemic arterial blood pressureIEA
GO:0005980glycogen catabolic processIEA
GO:0006915apoptosisIEA
GO:0007189activation of adenylate cyclase activity by G-protein signaling pathwayIEA
GO:0007190activation of adenylate cyclase activityTAS
GO:0007266Rho protein signal transductionIEA
GO:0007568agingIEA
GO:0007613memoryIEA
GO:0019233sensory perception of painIEA
GO:0030819positive regulation of cAMP biosynthetic processIDA
GO:0035811negative regulation of urine volumeIEA
GO:0042060wound healingIEA
GO:0042596fear responseIEA
GO:0045986negative regulation of smooth muscle contractionIEA
GO:0046878positive regulation of saliva secretionIEA
GO:0051929positive regulation of calcium ion transport via voltage-gated calcium channel activityIEA
GO:0060080regulation of inhibitory postsynaptic membrane potentialIEA
GO:0061051positive regulation of cell growth involved in cardiac muscle cell developmentIEA
cellular_component
GO:0005624membrane fractionIEA
GO:0005634nucleusIEA
GO:0005737cytoplasmIEA
GO:0005792microsomeIEA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneTAS
molecular_function
GO:0004871signal transducer activityIEA
GO:0004872receptor activityIEA
GO:0004930G-protein coupled receptor activityIEA
GO:0004939beta-adrenergic receptor activityTAS
GO:0004940beta1-adrenergic receptor activityIEA
GO:0005515protein bindingIPI
GO:0008144drug bindingIEA
GO:0031694alpha-2A adrenergic receptor bindingIPI
GO:0035240dopamine bindingIEA
GO:0046982protein heterodimerization activityIPI
GO:0051379epinephrine bindingIEA
GO:0051380norepinephrine bindingIEA

Protein-protein interaction details for ADRB1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
GIPC1Two-hybridphysical12724327
GIPC1Affinity Capture-Westernphysical12724327
ARRB1Reconstituted Complexphysical10862778
DLG4Affinity Capture-Westernphysical10995758
DLG4Reconstituted Complexphysical10995758
DLG4Two-hybridphysical10995758