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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for DAB2IP (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP GO:0007257 activation of JUN kinase activity IDA GO:0009967 positive regulation of signal transduction IDA GO:0010633 negative regulation of epithelial cell migration TAS GO:0010719 negative regulation of epithelial to mesenchymal transition IMP GO:0030308 negative regulation of cell growth IEA GO:0032088 negative regulation of NF-kappaB transcription factor activity IMP GO:0032320 positive regulation of Ras GTPase activity IBA GO:0032320 positive regulation of Ras GTPase activity ISS GO:0034261 negative regulation of Ras GTPase activity IMP GO:0035414 negative regulation of catenin import into nucleus IEA GO:0035414 negative regulation of catenin import into nucleus ISS GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway IEA GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway ISS GO:0043065 positive regulation of apoptosis IDA GO:0043065 positive regulation of apoptosis IEA GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade IDA GO:0043407 negative regulation of MAP kinase activity IDA GO:0043407 negative regulation of MAP kinase activity IMP GO:0043507 positive regulation of JUN kinase activity IDA GO:0043507 positive regulation of JUN kinase activity IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0046580 negative regulation of Ras protein signal transduction IBA GO:0046580 negative regulation of Ras protein signal transduction IC GO:0046580 negative regulation of Ras protein signal transduction IEA GO:0048147 negative regulation of fibroblast proliferation IEA GO:0048147 negative regulation of fibroblast proliferation ISS GO:0050680 negative regulation of epithelial cell proliferation IMP GO:0051056 regulation of small GTPase mediated signal transduction IEA GO:0070059 apoptosis in response to endoplasmic reticulum stress IEA GO:0070059 apoptosis in response to endoplasmic reticulum stress ISS GO:0071356 cellular response to tumor necrosis factor IDA GO:0071356 cellular response to tumor necrosis factor IEA GO:0071364 cellular response to epidermal growth factor stimulus IEA GO:0071364 cellular response to epidermal growth factor stimulus ISS GO:0071901 negative regulation of protein serine/threonine kinase activity IEA GO:0071901 negative regulation of protein serine/threonine kinase activity IMP GO:0071902 positive regulation of protein serine/threonine kinase activity IEA GO:0071902 positive regulation of protein serine/threonine kinase activity IMP GO:0090090 negative regulation of canonical Wnt receptor signaling pathway IMP cellular_component GO:0005622 intracellular IEA GO:0005737 cytoplasm IDA GO:0005886 plasma membrane IDA GO:0031235 intrinsic to internal side of plasma membrane IBA molecular_function GO:0005099 Ras GTPase activator activity IBA GO:0005099 Ras GTPase activator activity IEA GO:0005099 Ras GTPase activator activity ISS GO:0005123 death receptor binding IPI GO:0019901 protein kinase binding IPI GO:0031435 mitogen-activated protein kinase kinase kinase binding IPI GO:0035591 signaling adaptor activity IDA GO:0042803 protein homodimerization activity IPI GO:0047485 protein N-terminus binding IEA GO:0051721 protein phosphatase 2A binding IDA GO:0071889 14-3-3 protein binding IDA

Protein-protein interaction details for DAB2IP (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID DAB2 Affinity Capture-Western physical 11812785 DAB2 Reconstituted Complex physical 11812785 TP53 Affinity Capture-Western physical 20308539 TP63 Affinity Capture-Western physical 20308539 TP73 Affinity Capture-Western physical 20308539