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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Il10 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001818negative regulation of cytokine productionISO
GO:0002237response to molecule of bacterial originISO
GO:0002740negative regulation of cytokine secretion involved in immune responseISO
GO:0002875negative regulation of chronic inflammatory response to antigenic stimulusIMP
GO:0002904positive regulation of B cell apoptosisISO
GO:0006954inflammatory responseISO
GO:0006955immune responseISO
GO:0010468regulation of gene expressionISO
GO:0030886negative regulation of myeloid dendritic cell activationIMP
GO:0030889negative regulation of B cell proliferationISO
GO:0032689negative regulation of interferon-gamma productionIMP
GO:0032695negative regulation of interleukin-12 productionIMP
GO:0032715negative regulation of interleukin-6 productionISO
GO:0032720negative regulation of tumor necrosis factor productionIMP
GO:0032800receptor biosynthetic processISO
GO:0042536negative regulation of tumor necrosis factor biosynthetic processISO
GO:0042742defense response to bacteriumIDA
GO:0043066negative regulation of apoptosisISO
GO:0044130negative regulation of growth of symbiont in hostIMP
GO:0045019negative regulation of nitric oxide biosynthetic processISO
GO:0045348positive regulation of MHC class II biosynthetic processIDA
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentISO
GO:0050715positive regulation of cytokine secretionISO
GO:0050728negative regulation of inflammatory responseISO
GO:0051045negative regulation of membrane protein ectodomain proteolysisISO
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityISO
GO:0051384response to glucocorticoid stimulusISO
GO:0051930regulation of sensory perception of painISO
GO:0060670branching involved in embryonic placenta morphogenesisIMP
cellular_component
GO:0005576extracellular regionIEA
GO:0005615extracellular spaceIDA
GO:0005615extracellular spaceISO
molecular_function
GO:0005125cytokine activityIDA
GO:0005125cytokine activityIMP
GO:0005141interleukin-10 receptor bindingISO

Protein-protein interaction details for Il10 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Tlr4Phenotypic Suppressiongenetic19681597