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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Klf4 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006351transcription, DNA-dependentISO
GO:0006355regulation of transcription, DNA-dependentIEA
GO:0006357regulation of transcription from RNA polymerase II promoterIDA
GO:0006366transcription from RNA polymerase II promoterIDA
GO:0008285negative regulation of cell proliferationIDA
GO:0009913epidermal cell differentiationIMP
GO:0014067negative regulation of phosphatidylinositol 3-kinase cascadeISO
GO:0014740negative regulation of muscle hyperplasiaISO
GO:0019827stem cell maintenanceIDA
GO:0030154cell differentiationIMP
GO:0031077post-embryonic camera-type eye developmentIMP
GO:0032526response to retinoic acidIDA
GO:0042127regulation of cell proliferationIGI
GO:0042221response to chemical stimulusIDA
GO:0045444fat cell differentiationIMP
GO:0045595regulation of cell differentiationIDA
GO:0045892negative regulation of transcription, DNA-dependentISO
GO:0045892negative regulation of transcription, DNA-dependentISS
GO:0045892negative regulation of transcription, DNA-dependentNAS
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIMP
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0048662negative regulation of smooth muscle cell proliferationISO
GO:0048730epidermis morphogenesisIMP
GO:0051898negative regulation of protein kinase B signaling cascadeISO
GO:0070373negative regulation of ERK1 and ERK2 cascadeISO
cellular_component
GO:0000785chromatinISO
GO:0005622intracellularIEA
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0005634nucleusNAS
GO:0005667transcription factor complexISO
molecular_function
GO:0001010sequence-specific DNA binding transcription factor recruiting transcription factor activityIDA
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionISO
GO:0001085RNA polymerase II transcription factor bindingIPI
GO:0003676nucleic acid bindingIEA
GO:0003677DNA bindingISS
GO:0003690double-stranded DNA bindingISO
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0003700sequence-specific DNA binding transcription factor activityISO
GO:0008134transcription factor bindingIPI
GO:0008270zinc ion bindingIEA
GO:0035014phosphatidylinositol 3-kinase regulator activityISO
GO:0043565sequence-specific DNA bindingIDA
GO:0043565sequence-specific DNA bindingISO
GO:0044212transcription regulatory region DNA bindingIDA
GO:0044212transcription regulatory region DNA bindingISO
GO:0046872metal ion bindingIEA

Protein-protein interaction details for Klf4 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Pou5f1Affinity Capture-MSphysical20362542
ApcPhenotypic Enhancementgenetic17671182
TsixAffinity Capture-RNAphysical21085182