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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Lck (
Mus musculus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0006468
protein phosphorylation
IDA
GO:0006468
protein phosphorylation
IEA
GO:0006468
protein phosphorylation
ISO
GO:0006917
induction of apoptosis
ISO
GO:0006919
activation of caspase activity
ISO
GO:0007166
cell surface receptor linked signaling pathway
IDA
GO:0009612
response to mechanical stimulus
ISO
GO:0010038
response to metal ion
ISO
GO:0016310
phosphorylation
IEA
GO:0018108
peptidyl-tyrosine phosphorylation
IDA
GO:0018108
peptidyl-tyrosine phosphorylation
ISO
GO:0030217
T cell differentiation
ISO
GO:0042493
response to drug
ISO
GO:0042523
positive regulation of tyrosine phosphorylation of Stat5 protein
IDA
GO:0042542
response to hydrogen peroxide
ISO
GO:0045588
positive regulation of gamma-delta T cell differentiation
IMP
GO:0046777
protein autophosphorylation
IDA
GO:0046777
protein autophosphorylation
ISO
GO:0050853
B cell receptor signaling pathway
IDA
GO:0050856
regulation of T cell receptor signaling pathway
IDA
GO:0050870
positive regulation of T cell activation
ISO
GO:0051209
release of sequestered calcium ion into cytosol
IDA
GO:0070474
positive regulation of uterine smooth muscle contraction
ISO
cellular_component
GO:0000242
pericentriolar material
ISO
GO:0005737
cytoplasm
IEA
GO:0005794
Golgi apparatus
ISO
GO:0005886
plasma membrane
ISO
GO:0016020
membrane
IEA
GO:0030139
endocytic vesicle
ISO
GO:0045121
membrane raft
ISO
molecular_function
GO:0000166
nucleotide binding
IEA
GO:0001948
glycoprotein binding
ISO
GO:0003823
antigen binding
ISO
GO:0004672
protein kinase activity
IEA
GO:0004713
protein tyrosine kinase activity
IDA
GO:0004713
protein tyrosine kinase activity
ISO
GO:0004715
non-membrane spanning protein tyrosine kinase activity
IEA
GO:0004722
protein serine/threonine phosphatase activity
ISO
GO:0005515
protein binding
IPI
GO:0005524
ATP binding
IEA
GO:0008022
protein C-terminus binding
ISO
GO:0016301
kinase activity
IEA
GO:0016740
transferase activity
IEA
GO:0016772
transferase activity, transferring phosphorus-containing groups
IEA
GO:0019901
protein kinase binding
ISO
GO:0032403
protein complex binding
ISO
GO:0042169
SH2 domain binding
ISO
GO:0042609
CD4 receptor binding
ISO
GO:0042610
CD8 receptor binding
ISO
GO:0043548
phosphatidylinositol 3-kinase binding
ISO
GO:0051117
ATPase binding
ISO
Protein-protein interaction details for Lck (
Mus musculus
)
(Information is obtained from BioGRID)
Interacting mouse protein
Experiment
Type
PubMed ID
Cbl
Affinity Capture-Western
physical
11741956
Cd38
Affinity Capture-Western
physical
10636863
Zap70
Affinity Capture-Western
physical
16501569
Cyld
Affinity Capture-Western
physical
16501569
Ubc
Affinity Capture-Western
physical
16501569
Socs6
Two-hybrid
physical
20007709
Socs6
Reconstituted Complex
physical
20007709
Socs6
Affinity Capture-Western
physical
20007709