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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Map2k1 (
Rattus norvegicus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000165
MAPKKK cascade
IMP
GO:0000187
activation of MAPK activity
IDA
GO:0000187
activation of MAPK activity
ISO
GO:0002755
MyD88-dependent toll-like receptor signaling pathway
IEA
GO:0002756
MyD88-independent toll-like receptor signaling pathway
IEA
GO:0003056
regulation of vascular smooth muscle contraction
IMP
GO:0006468
protein phosphorylation
IDA
GO:0006468
protein phosphorylation
ISO
GO:0006468
protein phosphorylation
TAS
GO:0006979
response to oxidative stress
IDA
GO:0007050
cell cycle arrest
IEA
GO:0007050
cell cycle arrest
ISO
GO:0007067
mitosis
IDA
GO:0007243
intracellular protein kinase cascade
TAS
GO:0008283
cell proliferation
IDA
GO:0008285
negative regulation of cell proliferation
IEA
GO:0008285
negative regulation of cell proliferation
ISO
GO:0030182
neuron differentiation
IMP
GO:0030182
neuron differentiation
ISO
GO:0030216
keratinocyte differentiation
IEA
GO:0030216
keratinocyte differentiation
ISO
GO:0030335
positive regulation of cell migration
IMP
GO:0032320
positive regulation of Ras GTPase activity
IMP
GO:0032402
melanosome transport
IDA
GO:0032968
positive regulation of transcription elongation from RNA polymerase II promoter
IMP
GO:0034111
negative regulation of homotypic cell-cell adhesion
IMP
GO:0045597
positive regulation of cell differentiation
IEA
GO:0045597
positive regulation of cell differentiation
ISO
GO:0046579
positive regulation of Ras protein signal transduction
IMP
GO:0047496
vesicle transport along microtubule
IDA
GO:0048313
Golgi inheritance
IMP
GO:0048678
response to axon injury
IMP
GO:0048812
neuron projection morphogenesis
IMP
GO:0048870
cell motility
IEA
GO:0048870
cell motility
ISO
GO:0051291
protein heterooligomerization
IPI
GO:0051384
response to glucocorticoid stimulus
IDA
GO:0060674
placenta blood vessel development
IEA
GO:0060674
placenta blood vessel development
ISO
GO:0060711
labyrinthine layer development
IEA
GO:0060711
labyrinthine layer development
ISO
GO:0090398
cellular senescence
IEA
GO:0090398
cellular senescence
ISO
cellular_component
GO:0005625
soluble fraction
IDA
GO:0005737
cytoplasm
IEA
GO:0005737
cytoplasm
ISO
GO:0005794
Golgi apparatus
IDA
GO:0005829
cytosol
IDA
GO:0005829
cytosol
TAS
GO:0005874
microtubule
IDA
GO:0005886
plasma membrane
IDA
GO:0005886
plasma membrane
ISO
GO:0005938
cell cortex
IDA
GO:0030425
dendrite
IDA
GO:0032839
dendrite cytoplasm
IDA
GO:0033267
axon part
IDA
GO:0043204
perikaryon
IDA
GO:0048471
perinuclear region of cytoplasm
IDA
molecular_function
GO:0000166
nucleotide binding
IEA
GO:0004674
protein serine/threonine kinase activity
IEA
GO:0004708
MAP kinase kinase activity
IDA
GO:0004708
MAP kinase kinase activity
IMP
GO:0004708
MAP kinase kinase activity
ISO
GO:0004708
MAP kinase kinase activity
TAS
GO:0004713
protein tyrosine kinase activity
IEA
GO:0004728
receptor signaling protein tyrosine phosphatase activity
IEA
GO:0004728
receptor signaling protein tyrosine phosphatase activity
ISO
GO:0005515
protein binding
IPI
GO:0005524
ATP binding
IDA
GO:0017016
Ras GTPase binding
IPI
GO:0019901
protein kinase binding
IPI
GO:0031435
mitogen-activated protein kinase kinase kinase binding
IDA
GO:0031435
mitogen-activated protein kinase kinase kinase binding
IPI
Protein-protein interaction details for Map2k1 (
Rattus norvegicus
)
(Information is obtained from BioGRID)
Interacting protein
Experiment
Type
PubMed ID
Snca
Affinity Capture-Western
physical
10407019
Ksr1
Affinity Capture-Western
physical
10409742