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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Map2k1 (Rattus norvegicus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000165MAPKKK cascadeIMP
GO:0000187activation of MAPK activityIDA
GO:0000187activation of MAPK activityISO
GO:0002755MyD88-dependent toll-like receptor signaling pathwayIEA
GO:0002756MyD88-independent toll-like receptor signaling pathwayIEA
GO:0003056regulation of vascular smooth muscle contractionIMP
GO:0006468protein phosphorylationIDA
GO:0006468protein phosphorylationISO
GO:0006468protein phosphorylationTAS
GO:0006979response to oxidative stressIDA
GO:0007050cell cycle arrestIEA
GO:0007050cell cycle arrestISO
GO:0007067mitosisIDA
GO:0007243intracellular protein kinase cascadeTAS
GO:0008283cell proliferationIDA
GO:0008285negative regulation of cell proliferationIEA
GO:0008285negative regulation of cell proliferationISO
GO:0030182neuron differentiationIMP
GO:0030182neuron differentiationISO
GO:0030216keratinocyte differentiationIEA
GO:0030216keratinocyte differentiationISO
GO:0030335positive regulation of cell migrationIMP
GO:0032320positive regulation of Ras GTPase activityIMP
GO:0032402melanosome transportIDA
GO:0032968positive regulation of transcription elongation from RNA polymerase II promoterIMP
GO:0034111negative regulation of homotypic cell-cell adhesionIMP
GO:0045597positive regulation of cell differentiationIEA
GO:0045597positive regulation of cell differentiationISO
GO:0046579positive regulation of Ras protein signal transductionIMP
GO:0047496vesicle transport along microtubuleIDA
GO:0048313Golgi inheritanceIMP
GO:0048678response to axon injuryIMP
GO:0048812neuron projection morphogenesisIMP
GO:0048870cell motilityIEA
GO:0048870cell motilityISO
GO:0051291protein heterooligomerizationIPI
GO:0051384response to glucocorticoid stimulusIDA
GO:0060674placenta blood vessel developmentIEA
GO:0060674placenta blood vessel developmentISO
GO:0060711labyrinthine layer developmentIEA
GO:0060711labyrinthine layer developmentISO
GO:0090398cellular senescenceIEA
GO:0090398cellular senescenceISO
cellular_component
GO:0005625soluble fractionIDA
GO:0005737cytoplasmIEA
GO:0005737cytoplasmISO
GO:0005794Golgi apparatusIDA
GO:0005829cytosolIDA
GO:0005829cytosolTAS
GO:0005874microtubuleIDA
GO:0005886plasma membraneIDA
GO:0005886plasma membraneISO
GO:0005938cell cortexIDA
GO:0030425dendriteIDA
GO:0032839dendrite cytoplasmIDA
GO:0033267axon partIDA
GO:0043204perikaryonIDA
GO:0048471perinuclear region of cytoplasmIDA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004674protein serine/threonine kinase activityIEA
GO:0004708MAP kinase kinase activityIDA
GO:0004708MAP kinase kinase activityIMP
GO:0004708MAP kinase kinase activityISO
GO:0004708MAP kinase kinase activityTAS
GO:0004713protein tyrosine kinase activityIEA
GO:0004728receptor signaling protein tyrosine phosphatase activityIEA
GO:0004728receptor signaling protein tyrosine phosphatase activityISO
GO:0005515protein bindingIPI
GO:0005524ATP bindingIDA
GO:0017016Ras GTPase bindingIPI
GO:0019901protein kinase bindingIPI
GO:0031435mitogen-activated protein kinase kinase kinase bindingIDA
GO:0031435mitogen-activated protein kinase kinase kinase bindingIPI

Protein-protein interaction details for Map2k1 (Rattus norvegicus)
(Information is obtained from BioGRID)
Interacting proteinExperimentTypePubMed ID
SncaAffinity Capture-Westernphysical10407019
Ksr1Affinity Capture-Westernphysical10409742