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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Sphk1 (
Rattus norvegicus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001568
blood vessel development
IEA
GO:0001568
blood vessel development
ISO
GO:0001934
positive regulation of protein phosphorylation
IMP
GO:0001956
positive regulation of neurotransmitter secretion
IMP
GO:0006670
sphingosine metabolic process
IEA
GO:0006670
sphingosine metabolic process
ISO
GO:0006670
sphingosine metabolic process
ISS
GO:0006954
inflammatory response
IEA
GO:0006954
inflammatory response
ISO
GO:0007205
activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
IEA
GO:0007420
brain development
IEA
GO:0007420
brain development
ISO
GO:0007565
female pregnancy
IEP
GO:0008284
positive regulation of cell proliferation
ISO
GO:0009267
cellular response to starvation
IEP
GO:0010803
regulation of tumor necrosis factor-mediated signaling pathway
IEA
GO:0010803
regulation of tumor necrosis factor-mediated signaling pathway
ISO
GO:0010803
regulation of tumor necrosis factor-mediated signaling pathway
ISS
GO:0010976
positive regulation of neuron projection development
IMP
GO:0014070
response to organic cyclic compound
IEP
GO:0014075
response to amine stimulus
IEP
GO:0019371
cyclooxygenase pathway
IDA
GO:0019722
calcium-mediated signaling
IEA
GO:0019722
calcium-mediated signaling
ISO
GO:0030307
positive regulation of cell growth
IEA
GO:0030307
positive regulation of cell growth
ISO
GO:0030335
positive regulation of cell migration
IEA
GO:0030335
positive regulation of cell migration
IMP
GO:0030335
positive regulation of cell migration
ISO
GO:0031398
positive regulation of protein ubiquitination
IEA
GO:0031398
positive regulation of protein ubiquitination
ISO
GO:0031398
positive regulation of protein ubiquitination
ISS
GO:0032026
response to magnesium ion
IEP
GO:0032570
response to progesterone stimulus
IEP
GO:0032651
regulation of interleukin-1 beta production
IEA
GO:0032651
regulation of interleukin-1 beta production
ISO
GO:0033198
response to ATP
IEP
GO:0042346
positive regulation of NF-kappaB import into nucleus
IEA
GO:0042346
positive regulation of NF-kappaB import into nucleus
ISO
GO:0042346
positive regulation of NF-kappaB import into nucleus
ISS
GO:0043066
negative regulation of apoptosis
IEA
GO:0043066
negative regulation of apoptosis
IMP
GO:0043066
negative regulation of apoptosis
ISO
GO:0045766
positive regulation of angiogenesis
IEA
GO:0045766
positive regulation of angiogenesis
ISO
GO:0045931
positive regulation of mitotic cell cycle
IEA
GO:0045931
positive regulation of mitotic cell cycle
ISO
GO:0045987
positive regulation of smooth muscle contraction
IEA
GO:0045987
positive regulation of smooth muscle contraction
ISO
GO:0048146
positive regulation of fibroblast proliferation
IEA
GO:0048146
positive regulation of fibroblast proliferation
ISO
GO:0051092
positive regulation of NF-kappaB transcription factor activity
IEA
GO:0051092
positive regulation of NF-kappaB transcription factor activity
ISO
GO:0051092
positive regulation of NF-kappaB transcription factor activity
ISS
GO:0070301
cellular response to hydrogen peroxide
IEP
GO:0070555
response to interleukin-1
IEP
GO:0071363
cellular response to growth factor stimulus
IEP
cellular_component
GO:0005624
membrane fraction
IEA
GO:0005624
membrane fraction
ISO
GO:0005625
soluble fraction
IEA
GO:0005625
soluble fraction
ISO
GO:0005634
nucleus
IEA
GO:0005737
cytoplasm
IEA
GO:0005737
cytoplasm
ISO
GO:0005829
cytosol
IDA
GO:0005886
plasma membrane
IDA
GO:0005886
plasma membrane
ISO
GO:0008021
synaptic vesicle
IDA
GO:0030424
axon
IDA
GO:0043005
neuron projection
IDA
molecular_function
GO:0000166
nucleotide binding
IEA
GO:0000287
magnesium ion binding
ISO
GO:0000287
magnesium ion binding
ISS
GO:0003677
DNA binding
IEA
GO:0003677
DNA binding
ISO
GO:0004143
diacylglycerol kinase activity
IEA
GO:0005515
protein binding
IPI
GO:0005516
calmodulin binding
IEA
GO:0005516
calmodulin binding
ISO
GO:0005524
ATP binding
IEA
GO:0005524
ATP binding
ISO
GO:0008481
sphinganine kinase activity
IEA
GO:0008481
sphinganine kinase activity
ISO
GO:0016740
transferase activity
IEA
GO:0017050
D-erythro-sphingosine kinase activity
IDA
GO:0017050
D-erythro-sphingosine kinase activity
IEA
GO:0017050
D-erythro-sphingosine kinase activity
ISO
GO:0017050
D-erythro-sphingosine kinase activity
ISS
GO:0051721
protein phosphatase 2A binding
IEA
GO:0051721
protein phosphatase 2A binding
ISO
Protein-protein interaction details for Sphk1 (
Rattus norvegicus
)
(Information is obtained from BioGRID)
Not available