Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Smad6 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006351transcription, DNA-dependentIEA
GO:0006355regulation of transcription, DNA-dependentIEA
GO:0006955immune responseISO
GO:0007179transforming growth factor beta receptor signaling pathwayIEA
GO:0007352zygotic specification of dorsal/ventral axisISO
GO:0010991negative regulation of SMAD protein complex assemblyISO
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathwayISO
GO:0030514negative regulation of BMP signaling pathwayISO
GO:0031589cell-substrate adhesionISO
GO:0043066negative regulation of apoptosisISO
GO:0043154negative regulation of caspase activityISO
GO:0045750positive regulation of S phase of mitotic cell cycleISO
GO:0060394negative regulation of pathway-restricted SMAD protein phosphorylationISO
cellular_component
GO:0005622intracellularIEA
GO:0005634nucleusISO
GO:0005667transcription factor complexIEA
molecular_function
GO:0003682chromatin bindingISO
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0005515protein bindingIPI
GO:0030617transforming growth factor beta receptor, inhibitory cytoplasmic mediator activityISO
GO:0031625ubiquitin protein ligase bindingISO
GO:0034713type I transforming growth factor beta receptor bindingISO
GO:0044212transcription regulatory region DNA bindingISO
GO:0070410co-SMAD bindingISO
GO:0070411I-SMAD bindingISO
GO:0070412R-SMAD bindingISO
GO:0070698type I activin receptor bindingISO

Protein-protein interaction details for Smad6 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Axin1Affinity Capture-Westernphysical16601693
Axin1Affinity Capture-Westernphysical16601693