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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Smad7 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterISO
GO:0006351transcription, DNA-dependentIEA
GO:0006355regulation of transcription, DNA-dependentIEA
GO:0007179transforming growth factor beta receptor signaling pathwayIDA
GO:0010801negative regulation of peptidyl-threonine phosphorylationISO
GO:0010944negative regulation of transcription by competitive promoter bindingISO
GO:0017015regulation of transforming growth factor beta receptor signaling pathwayIC
GO:0017015regulation of transforming growth factor beta receptor signaling pathwayISO
GO:0022409positive regulation of cell-cell adhesionISO
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathwayISO
GO:0030514negative regulation of BMP signaling pathwayIDA
GO:0030514negative regulation of BMP signaling pathwayISO
GO:0031397negative regulation of protein ubiquitinationISO
GO:0031398positive regulation of protein ubiquitinationISO
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic processISO
GO:0032925regulation of activin receptor signaling pathwayISO
GO:0033137negative regulation of peptidyl-serine phosphorylationISO
GO:0034333adherens junction assemblyISO
GO:0034629cellular protein complex localizationISO
GO:0035556intracellular signal transductionISO
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activityISO
GO:0048844artery morphogenesisIMP
GO:0050821protein stabilizationISO
GO:0051444negative regulation of ubiquitin-protein ligase activityISO
GO:0055010ventricular cardiac muscle tissue morphogenesisIMP
GO:0055117regulation of cardiac muscle contractionIMP
GO:0060373regulation of ventricular cardiomyocyte membrane depolarizationIC
GO:0060389pathway-restricted SMAD protein phosphorylationIMP
GO:0060394negative regulation of pathway-restricted SMAD protein phosphorylationISO
GO:0060412ventricular septum morphogenesisIMP
cellular_component
GO:0005622intracellularISO
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0005667transcription factor complexIEA
GO:0005730nucleolusISO
GO:0005737cytoplasmISO
GO:0005813centrosomeISO
GO:0005886plasma membraneISO
GO:0043234protein complexIDA
molecular_function
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0005515protein bindingIPI
GO:0005518collagen bindingIPI
GO:0008013beta-catenin bindingISO
GO:0030617transforming growth factor beta receptor, inhibitory cytoplasmic mediator activityISO
GO:0031625ubiquitin protein ligase bindingISO
GO:0034713type I transforming growth factor beta receptor bindingISO
GO:0044212transcription regulatory region DNA bindingISO
GO:0048185activin bindingISO
GO:0070411I-SMAD bindingISO

Protein-protein interaction details for Smad7 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Axin1Affinity Capture-Westernphysical16601693
Axin1Affinity Capture-Westernphysical16601693
Rnf111Affinity Capture-Westernphysical16601693
Axin2Affinity Capture-Westernphysical16601693
Axin1Co-localizationphysical16601693