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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Smad7 (
Mus musculus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
ISO
GO:0006351
transcription, DNA-dependent
IEA
GO:0006355
regulation of transcription, DNA-dependent
IEA
GO:0007179
transforming growth factor beta receptor signaling pathway
IDA
GO:0010801
negative regulation of peptidyl-threonine phosphorylation
ISO
GO:0010944
negative regulation of transcription by competitive promoter binding
ISO
GO:0017015
regulation of transforming growth factor beta receptor signaling pathway
IC
GO:0017015
regulation of transforming growth factor beta receptor signaling pathway
ISO
GO:0022409
positive regulation of cell-cell adhesion
ISO
GO:0030512
negative regulation of transforming growth factor beta receptor signaling pathway
ISO
GO:0030514
negative regulation of BMP signaling pathway
IDA
GO:0030514
negative regulation of BMP signaling pathway
ISO
GO:0031397
negative regulation of protein ubiquitination
ISO
GO:0031398
positive regulation of protein ubiquitination
ISO
GO:0032436
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
ISO
GO:0032925
regulation of activin receptor signaling pathway
ISO
GO:0033137
negative regulation of peptidyl-serine phosphorylation
ISO
GO:0034333
adherens junction assembly
ISO
GO:0034629
cellular protein complex localization
ISO
GO:0035556
intracellular signal transduction
ISO
GO:0043433
negative regulation of sequence-specific DNA binding transcription factor activity
ISO
GO:0048844
artery morphogenesis
IMP
GO:0050821
protein stabilization
ISO
GO:0051444
negative regulation of ubiquitin-protein ligase activity
ISO
GO:0055010
ventricular cardiac muscle tissue morphogenesis
IMP
GO:0055117
regulation of cardiac muscle contraction
IMP
GO:0060373
regulation of ventricular cardiomyocyte membrane depolarization
IC
GO:0060389
pathway-restricted SMAD protein phosphorylation
IMP
GO:0060394
negative regulation of pathway-restricted SMAD protein phosphorylation
ISO
GO:0060412
ventricular septum morphogenesis
IMP
cellular_component
GO:0005622
intracellular
ISO
GO:0005634
nucleus
IDA
GO:0005634
nucleus
ISO
GO:0005667
transcription factor complex
IEA
GO:0005730
nucleolus
ISO
GO:0005737
cytoplasm
ISO
GO:0005813
centrosome
ISO
GO:0005886
plasma membrane
ISO
GO:0043234
protein complex
IDA
molecular_function
GO:0003700
sequence-specific DNA binding transcription factor activity
IEA
GO:0005515
protein binding
IPI
GO:0005518
collagen binding
IPI
GO:0008013
beta-catenin binding
ISO
GO:0030617
transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
ISO
GO:0031625
ubiquitin protein ligase binding
ISO
GO:0034713
type I transforming growth factor beta receptor binding
ISO
GO:0044212
transcription regulatory region DNA binding
ISO
GO:0048185
activin binding
ISO
GO:0070411
I-SMAD binding
ISO
Protein-protein interaction details for Smad7 (
Mus musculus
)
(Information is obtained from BioGRID)
Interacting mouse protein
Experiment
Type
PubMed ID
Axin1
Affinity Capture-Western
physical
16601693
Axin1
Affinity Capture-Western
physical
16601693
Rnf111
Affinity Capture-Western
physical
16601693
Axin2
Affinity Capture-Western
physical
16601693
Axin1
Co-localization
physical
16601693