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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Mdm2 (Mus musculus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISO GO:0006461 protein complex assembly ISO GO:0007089 traversing start control point of mitotic cell cycle IDA GO:0010628 positive regulation of gene expression ISO GO:0010629 negative regulation of gene expression ISO GO:0010955 negative regulation of protein processing ISO GO:0016567 protein ubiquitination IDA GO:0016567 protein ubiquitination ISO GO:0030163 protein catabolic process IDA GO:0031648 protein destabilization ISO GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process ISO GO:0034504 protein localization to nucleus ISO GO:0042176 regulation of protein catabolic process ISO GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ISO GO:0043066 negative regulation of apoptosis ISO GO:0043154 negative regulation of caspase activity ISO GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator ISO GO:0045184 establishment of protein localization ISO GO:0045787 positive regulation of cell cycle IGI GO:0045892 negative regulation of transcription, DNA-dependent ISO GO:0045931 positive regulation of mitotic cell cycle ISO GO:0046827 positive regulation of protein export from nucleus ISO GO:0071157 negative regulation of cell cycle arrest ISO cellular_component GO:0005622 intracellular IEA GO:0005625 soluble fraction ISO GO:0005626 insoluble fraction ISO GO:0005634 nucleus IDA GO:0005634 nucleus ISO GO:0005654 nucleoplasm ISO GO:0005730 nucleolus IDA GO:0005730 nucleolus ISO GO:0005737 cytoplasm IDA GO:0005829 cytosol ISO GO:0005886 plasma membrane ISO GO:0043234 protein complex ISO GO:0045202 synapse ISO molecular_function GO:0002039 p53 binding IPI GO:0002039 p53 binding ISO GO:0004842 ubiquitin-protein ligase activity IDA GO:0004842 ubiquitin-protein ligase activity ISO GO:0005515 protein binding IPI GO:0008270 zinc ion binding ISO GO:0016874 ligase activity IEA GO:0019899 enzyme binding ISO GO:0042975 peroxisome proliferator activated receptor binding ISO GO:0046872 metal ion binding IEA

Protein-protein interaction details for Mdm2 (Mus musculus) (Information is obtained from BioGRID)

Interacting mouse protein Experiment Type PubMed ID Ubc Affinity Capture-Western physical 18566590 Rassf1 Affinity Capture-Western physical 18566590 Trp53 Affinity Capture-Western physical 18566590 Rassf1 Reconstituted Complex physical 18566590 Mdm2 Biochemical Activity physical 18566590 Daxx Affinity Capture-Western physical 18566590 Trp53 Affinity Capture-Western physical 18309296 Trp53 Affinity Capture-Western physical 17936560 Trp53 Affinity Capture-Western physical 17936560 Arrb2 Biochemical Activity physical 11588219 Dlg4 Affinity Capture-Western physical 21849563 AF366264 Affinity Capture-MS physical 17086174 AF366264 Reconstituted Complex physical 17086174 AF366264 Affinity Capture-Western physical 17086174 AF366264 Co-localization physical 17086174 Mdm2 Biochemical Activity physical 17086174 AF366264 Affinity Capture-Western physical 17086174 Trp53 Affinity Capture-Western physical 17086174 Ubc Affinity Capture-Western physical 17086174 Sumo1 Affinity Capture-Western physical 17086174 Trp53 Affinity Capture-Western physical 17086174 AF366264 Biochemical Activity physical 17086174 Trp53 Biochemical Activity physical 17086174 Foxo3 Affinity Capture-Western physical 22094330 Trp53 Affinity Capture-Western physical 20697359 Mdm4 Affinity Capture-Western physical 20697359 Usp7 Affinity Capture-Western physical 20697359 Pax3 Affinity Capture-Western physical 22216266 Pax3 Reconstituted Complex physical 22216266 Trp53 Affinity Capture-Western physical 22216266 Pax3 Affinity Capture-Western physical 22216266 Trp53 Affinity Capture-Western physical 22216266 Trp53 Biochemical Activity physical 22216266 Usp7 Affinity Capture-Western physical 18566590 Daxx Affinity Capture-Western physical 18566590 Senp2 Affinity Capture-Western physical 21183956 Senp2 Affinity Capture-Western physical 21183956 Senp2 Biochemical Activity physical 21183956 Sumo1 Affinity Capture-Western physical 21183956 Trp53 Biochemical Activity physical 21183956 Ube2i Biochemical Activity physical 21183956 Ubc Affinity Capture-Western physical 21730132 Mdm4 Affinity Capture-Western physical 21730132