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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for DLG4 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006461 protein complex assembly IDA GO:0007165 signal transduction TAS GO:0007268 synaptic transmission TAS GO:0007399 nervous system development TAS GO:0007411 axon guidance TAS GO:0007612 learning TAS GO:0016188 synaptic vesicle maturation IEA GO:0035418 protein localization to synapse IDA GO:0045184 establishment of protein localization IDA GO:0048169 regulation of long-term neuronal synaptic plasticity IEA GO:0060997 dendritic spine morphogenesis ISS GO:0097113 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering ISS GO:0097113 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering TAS GO:0097120 receptor localization to synapse ISS cellular_component GO:0005737 cytoplasm IEA GO:0005886 plasma membrane TAS GO:0014069 postsynaptic density IEA GO:0014069 postsynaptic density ISS GO:0019717 synaptosome IEA GO:0019717 synaptosome ISS GO:0030054 cell junction IEA GO:0030666 endocytic vesicle membrane TAS GO:0030863 cortical cytoskeleton IDA GO:0031234 extrinsic to internal side of plasma membrane IEA GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex IEA GO:0032839 dendrite cytoplasm ISS GO:0044224 juxtaparanode region of axon IEA GO:0044306 neuron projection terminus IEA GO:0044309 neuron spine IEA GO:0044309 neuron spine ISS GO:0045202 synapse IDA GO:0045211 postsynaptic membrane IDA GO:0045211 postsynaptic membrane IEA GO:0060076 excitatory synapse IEA GO:0060076 excitatory synapse ISS molecular_function GO:0005102 receptor binding IEA GO:0005515 protein binding IPI GO:0008022 protein C-terminus binding IEA GO:0008022 protein C-terminus binding IPI GO:0019903 protein phosphatase binding IEA GO:0030165 PDZ domain binding IEA GO:0035255 ionotropic glutamate receptor binding IEA GO:0097110 scaffold protein binding ISS

Protein-protein interaction details for DLG4 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID KCNJ4 Two-hybrid physical 10627592 ERBB4 Two-hybrid physical 10725395 KCNJ2 Two-hybrid physical 10627592 ACCN3 Affinity Capture-Western physical 15317815 KCNJ12 Affinity Capture-MS physical 15024025 KCNJ12 Affinity Capture-Western physical 15024025 KCNJ12 Affinity Capture-Western physical 14960569 KCNJ4 Affinity Capture-Western physical 14960569 KCNA5 Affinity Capture-Western physical 12860415 GRIN2B Affinity Capture-Western physical 12738960 EXOC4 Affinity Capture-Western physical 12738960 LRP2 Affinity Capture-Western physical 12713445 LRP2 Two-hybrid physical 12713445 HTR2A Affinity Capture-Western physical 12682061 EXOC4 Reconstituted Complex physical 12675619 EXOC4 Reconstituted Complex physical 12675619 EXOC4 Affinity Capture-Western physical 12675619 GRIK1 Reconstituted Complex physical 12597860 GRIK2 Reconstituted Complex physical 12597860 GRIK2 Affinity Capture-Western physical 12597860 GRIK1 Affinity Capture-Western physical 12597860 ADAM22 Affinity Capture-MS physical 16990550 LGI1 Affinity Capture-MS physical 16990550 ADAM22 Affinity Capture-Western physical 16990550 LGI1 Affinity Capture-Western physical 16990550 ADAM22 Affinity Capture-Western physical 16990550 ADAM22 Affinity Capture-MS physical 16990550 GRIA2 Affinity Capture-MS physical 16990550 GRIA3 Affinity Capture-MS physical 16990550 PTK2B Affinity Capture-Western physical 12576483 PTK2B Reconstituted Complex physical 12576483 CACNG2 Affinity Capture-Western physical 11140673 CACNG2 Co-fractionation physical 11140673 FYN Affinity Capture-Western physical 9892651 LRP2 Two-hybrid physical 10827173 LRP1 Two-hybrid physical 10827173 LRP8 Two-hybrid physical 10827173 LRP2 Reconstituted Complex physical 10827173 LRP1 Reconstituted Complex physical 10827173 KCNJ4 Affinity Capture-Western physical 11997254 GRIN2B Affinity Capture-Western physical 11997254 KCNA4 Affinity Capture-Western physical 11997254 CASK Affinity Capture-Western physical 12151521 HGS Two-hybrid physical 12151521 HGS Affinity Capture-Western physical 12151521 CASK Two-hybrid physical 12151521 SYNGAP1 Two-hybrid physical 9581761 DYNLL2 Reconstituted Complex physical 10844022 DYNLL1 Reconstituted Complex physical 10844022 DLGAP1 Affinity Capture-Western physical 10844022 DYNLL1 Affinity Capture-Western physical 10844022 DYNLL2 Affinity Capture-Western physical 10844022 SHANK2 Affinity Capture-Western physical 10844022 DLG3 Two-hybrid physical 10026200 DLG3 Reconstituted Complex physical 10026200 ERBB2 Two-hybrid physical 10839362 ERBB2 Affinity Capture-Western physical 10839362 ERBB4 Affinity Capture-Western physical 10839362 ERBB2 Co-fractionation physical 10839362 ERBB4 Co-fractionation physical 10839362 DLG4 Affinity Capture-Western physical 9182804 DLG2 Affinity Capture-Western physical 9182804 ERBB4 Affinity Capture-Western physical 10725395 ERBB4 Affinity Capture-Western physical 10725395 DLGAP1 Reconstituted Complex physical 9115257 DLGAP1 Co-fractionation physical 9115257 DLGAP2 Two-hybrid physical 9115257 DLGAP3 Two-hybrid physical 9115257 DLGAP4 Two-hybrid physical 9115257 DLGAP2 Reconstituted Complex physical 9115257 PARK2 Affinity Capture-Western physical 11679592 GRIN2A Affinity Capture-Western physical 12419528 FYN Affinity Capture-Western physical 12419528 GRIN2A Affinity Capture-Western physical 12419528 FYN Affinity Capture-Western physical 12419528 NLGN2 Two-hybrid physical 9278515 NLGN1 Two-hybrid physical 9278515 NLGN3 Two-hybrid physical 9278515 GRIN2A Two-hybrid physical 9278515 GRIN2B Two-hybrid physical 9278515 NLGN1 Reconstituted Complex physical 9278515 GRIN2A Reconstituted Complex physical 9278515 DLG1 Affinity Capture-Western physical 9286858 DLGAP1 Affinity Capture-Western physical 9286858 GRIN2A Affinity Capture-Western physical 9286858 DLGAP1 Affinity Capture-Western physical 9286858 KCNA4 Reconstituted Complex physical 9581762 GRIN2B Reconstituted Complex physical 9581762 CRIPT Reconstituted Complex physical 9581762 GRIK2 Affinity Capture-Western physical 11279111 GRIK5 Affinity Capture-Western physical 11279111 LRRC7 Affinity Capture-Western physical 12390249 ADRB1 Affinity Capture-Western physical 10995758 ADRB1 Reconstituted Complex physical 10995758 ADRB1 Two-hybrid physical 10995758 GRIN2A Affinity Capture-Western physical 10648730 PTPRG Two-hybrid physical 10521598 SEMA4C Two-hybrid physical 11134026 SEMA4C Affinity Capture-Western physical 11134026 SEMA4C Reconstituted Complex physical 11134026 HTR2C Reconstituted Complex physical 12006486 LRRC1 Two-hybrid physical 11440998 CACNG2 Affinity Capture-Western physical 11805122 KCNA4 Two-hybrid physical 8938729 KCNA4 Affinity Capture-Western physical 8938729 NLGN4X Affinity Capture-Western physical 11368788 MAP1A Two-hybrid physical 9786987 GRIK2 Affinity Capture-Western physical 9808460 GRIK5 Affinity Capture-Western physical 9808460 GRIK5 Reconstituted Complex physical 9808460 GRIK2 Reconstituted Complex physical 9808460 SHANK2 Affinity Capture-Western physical 10527873 DLGAP1 Affinity Capture-Western physical 10527873 NOS1 Affinity Capture-Western physical 9459447 NOS1 Two-hybrid physical 8625413 NOS1 Reconstituted Complex physical 8625413 NOS1 Co-purification physical 8625413 FZD1 Two-hybrid physical 12067714 FZD2 Two-hybrid physical 12067714 FZD4 Two-hybrid physical 12067714 FZD7 Two-hybrid physical 12067714 FZD7 Affinity Capture-Western physical 12067714 DLGAP1 Reconstituted Complex physical 11060025 MAP3K10 Affinity Capture-Western physical 11152698 MAP3K11 Affinity Capture-Western physical 11152698 DLGAP1 Two-hybrid physical 9024696 DLGAP1 Far Western physical 9024696 DLGAP1 Affinity Capture-Western physical 9024696 DLGAP1 Affinity Capture-Western physical 9024696 KCND2 Two-hybrid physical 12435606 KCNA1 Two-hybrid physical 12435606 KCNA5 Two-hybrid physical 12435606 KCNA4 Two-hybrid physical 12435606 KCNA2 Two-hybrid physical 12435606 KCNA2 Reconstituted Complex physical 12435606 KCNA4 Reconstituted Complex physical 12435606 KCNA5 Reconstituted Complex physical 12435606 KCNA1 Reconstituted Complex physical 12435606 KCNA5 Affinity Capture-Western physical 12435606 KCNA4 Affinity Capture-Western physical 12435606 ACTN2 Reconstituted Complex physical 12435606 KIF13B Reconstituted Complex physical 10859302 KCNJ4 Affinity Capture-Western physical 10627592 KCNJ2 Affinity Capture-Western physical 10627592 BAI1 Affinity Capture-Western physical 11937501 PRKCA Affinity Capture-Western physical 11937501 GRIN2A Affinity Capture-Western physical 11937501 GRIN2C Affinity Capture-Western physical 11937501 GRIN2C Reconstituted Complex physical 11937501 GRIN2A Reconstituted Complex physical 11937501 GRIN2B Reconstituted Complex physical 11937501 LIN7A Reconstituted Complex physical 10341223 LIN7B Affinity Capture-Western physical 10341223 GUCY1A2 Affinity Capture-Western physical 11572861 CD46 Two-hybrid physical 11714708 GRIN2B Affinity Capture-Western physical 7569905 GRIN2B Reconstituted Complex physical 7569905