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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for DOCK1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006911 phagocytosis, engulfment TAS GO:0006915 apoptosis IEA GO:0007165 signal transduction TAS GO:0007229 integrin-mediated signaling pathway TAS GO:0007264 small GTPase mediated signal transduction TAS GO:0007411 axon guidance TAS GO:0007596 blood coagulation TAS GO:0016477 cell migration IEA GO:0043547 positive regulation of GTPase activity TAS cellular_component GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0016020 membrane IEA molecular_function GO:0005085 guanyl-nucleotide exchange factor activity IEA GO:0005096 GTPase activator activity TAS GO:0005515 protein binding IPI GO:0005525 GTP binding IEA GO:0017124 SH3 domain binding IEA GO:0051020 GTPase binding IEA

Protein-protein interaction details for DOCK1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID RHOG Affinity Capture-Western physical 12879077 BCAR1 Reconstituted Complex physical 12615911 CRK Reconstituted Complex physical 12615911 GRB2 Reconstituted Complex physical 12615911 CRK Affinity Capture-Western physical 12615911 BCAR1 Affinity Capture-Western physical 12615911 CRK Affinity Capture-Western physical 12615911 SRC Affinity Capture-Western physical 12615911 BCAR1 Affinity Capture-Western physical 12615911 PTK2 Affinity Capture-Western physical 12615911 CRK Affinity Capture-Western physical 10559471 CRK Co-fractionation physical 8657152 GRB2 Co-fractionation physical 8657152 CRK Affinity Capture-Western physical 8657152 CRK Affinity Capture-Western physical 11369773 ELMO1 Affinity Capture-Western physical 11595183 CRK Reconstituted Complex physical 8662907 RAC1 Reconstituted Complex physical 9808620 ELMO1 Affinity Capture-Western physical 12134158 NCK2 Reconstituted Complex physical 11240126 MEPCE Affinity Capture-MS physical 17643375 UBC Affinity Capture-Western physical 16495483 ELMO1 Affinity Capture-Western physical 16495483 MAP1LC3B Affinity Capture-MS physical 20562859 GRB2 Two-hybrid physical 20936779