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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Nf1 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000165MAPKKK cascadeIMP
GO:0001649osteoblast differentiationIMP
GO:0001656metanephros developmentIMP
GO:0001666response to hypoxiaIMP
GO:0001889liver developmentIMP
GO:0001937negative regulation of endothelial cell proliferationIMP
GO:0001937negative regulation of endothelial cell proliferationISO
GO:0001938positive regulation of endothelial cell proliferationIGI
GO:0001952regulation of cell-matrix adhesionIMP
GO:0001953negative regulation of cell-matrix adhesionIGI
GO:0006469negative regulation of protein kinase activityIGI
GO:0006469negative regulation of protein kinase activityIMP
GO:0007154cell communicationIMP
GO:0007165signal transductionIEA
GO:0007265Ras protein signal transductionIGI
GO:0007265Ras protein signal transductionIMP
GO:0007406negative regulation of neuroblast proliferationIMP
GO:0007420brain developmentIMP
GO:0007422peripheral nervous system developmentIMP
GO:0007507heart developmentIMP
GO:0007519skeletal muscle tissue developmentIMP
GO:0008285negative regulation of cell proliferationIGI
GO:0008285negative regulation of cell proliferationIMP
GO:0008542visual learningIGI
GO:0008542visual learningIMP
GO:0014044Schwann cell developmentIMP
GO:0014065phosphatidylinositol 3-kinase cascadeIMP
GO:0016525negative regulation of angiogenesisIGI
GO:0021510spinal cord developmentIMP
GO:0021897forebrain astrocyte developmentIMP
GO:0021915neural tube developmentIGI
GO:0021987cerebral cortex developmentIMP
GO:0022011myelination in peripheral nervous systemIMP
GO:0030036actin cytoskeleton organizationIGI
GO:0030036actin cytoskeleton organizationIMP
GO:0030198extracellular matrix organizationIMP
GO:0030199collagen fibril organizationIMP
GO:0030325adrenal gland developmentIMP
GO:0030336negative regulation of cell migrationIGI
GO:0030336negative regulation of cell migrationIMP
GO:0030336negative regulation of cell migrationISO
GO:0032228regulation of synaptic transmission, GABAergicIGI
GO:0032318regulation of Ras GTPase activityISO
GO:0032320positive regulation of Ras GTPase activityIMP
GO:0032320positive regulation of Ras GTPase activityISO
GO:0035021negative regulation of Rac protein signal transductionIGI
GO:0042060wound healingIMP
GO:0042127regulation of cell proliferationIGI
GO:0042992negative regulation of transcription factor import into nucleusIMP
GO:0043065positive regulation of apoptosisIGI
GO:0043065positive regulation of apoptosisIMP
GO:0043407negative regulation of MAP kinase activityIGI
GO:0043407negative regulation of MAP kinase activityIMP
GO:0043409negative regulation of MAPKKK cascadeIMP
GO:0043409negative regulation of MAPKKK cascadeISO
GO:0043473pigmentationIGI
GO:0043473pigmentationIMP
GO:0043525positive regulation of neuron apoptosisIGI
GO:0043525positive regulation of neuron apoptosisIMP
GO:0043535regulation of blood vessel endothelial cell migrationISO
GO:0045124regulation of bone resorptionIMP
GO:0045664regulation of neuron differentiationISO
GO:0045671negative regulation of osteoclast differentiationIGI
GO:0045685regulation of glial cell differentiationIMP
GO:0045762positive regulation of adenylate cyclase activityIMP
GO:0045765regulation of angiogenesisIMP
GO:0045765regulation of angiogenesisISO
GO:0046580negative regulation of Ras protein signal transductionIGI
GO:0046580negative regulation of Ras protein signal transductionIMP
GO:0046929negative regulation of neurotransmitter secretionIGI
GO:0046929negative regulation of neurotransmitter secretionIMP
GO:0048147negative regulation of fibroblast proliferationIMP
GO:0048169regulation of long-term neuronal synaptic plasticityIGI
GO:0048169regulation of long-term neuronal synaptic plasticityIMP
GO:0048485sympathetic nervous system developmentIMP
GO:0048593camera-type eye morphogenesisIMP
GO:0048712negative regulation of astrocyte differentiationIMP
GO:0048715negative regulation of oligodendrocyte differentiationIMP
GO:0048745smooth muscle tissue developmentIMP
GO:0048844artery morphogenesisIMP
GO:0048853forebrain morphogenesisIMP
GO:0050890cognitionISO
GO:0051056regulation of small GTPase mediated signal transductionIEA
cellular_component
GO:0005622intracellularIEA
GO:0005624membrane fractionISO
GO:0005634nucleusISO
GO:0005737cytoplasmIDA
GO:0005737cytoplasmISO
GO:0014069postsynaptic densityISO
GO:0019717synaptosomeISO
GO:0030424axonISO
GO:0030425dendriteISO
GO:0031235intrinsic to internal side of plasma membraneIBA
GO:0043234protein complexISO
molecular_function
GO:0005096GTPase activator activityIMP
GO:0005099Ras GTPase activator activityIBA
GO:0005099Ras GTPase activator activityIGI
GO:0005099Ras GTPase activator activityISO
GO:0005488bindingIEA
GO:0005515protein bindingIPI
GO:0008017microtubule bindingISO
GO:0045545syndecan bindingISO

Protein-protein interaction details for Nf1 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Polr2aAffinity Capture-Westernphysical15999204
Smarca4Affinity Capture-Westernphysical15999204
Smarca4Affinity Capture-Westernphysical15999204
Polr2aAffinity Capture-Westernphysical15999204
YwhaeAffinity Capture-MSphysical16944949