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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Nkx2-2 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0003323type B pancreatic cell developmentIDA
GO:0003323type B pancreatic cell developmentIMP
GO:0003326pancreatic A cell fate commitmentIGI
GO:0003326pancreatic A cell fate commitmentIMP
GO:0003327type B pancreatic cell fate commitmentIMP
GO:0003329pancreatic PP cell fate commitmentIGI
GO:0006351transcription, DNA-dependentIEA
GO:0006355regulation of transcription, DNA-dependentIDA
GO:0007224smoothened signaling pathwayIDA
GO:0007275multicellular organismal developmentIEA
GO:0007399nervous system developmentIDA
GO:0014003oligodendrocyte developmentIMP
GO:0021522spinal cord motor neuron differentiationIMP
GO:0021529spinal cord oligodendrocyte cell differentiationIGI
GO:0021529spinal cord oligodendrocyte cell differentiationIMP
GO:0021530spinal cord oligodendrocyte cell fate specificationIDA
GO:0030154cell differentiationIMP
GO:0031018endocrine pancreas developmentIMP
GO:0045595regulation of cell differentiationIMP
GO:0045597positive regulation of cell differentiationIMP
GO:0045665negative regulation of neuron differentiationIDA
GO:0045665negative regulation of neuron differentiationIMP
GO:0045666positive regulation of neuron differentiationIDA
GO:0045666positive regulation of neuron differentiationIMP
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0048468cell developmentIMP
GO:0048565digestive tract developmentIMP
GO:0048665neuron fate specificationIGI
GO:0048708astrocyte differentiationIMP
GO:0048714positive regulation of oligodendrocyte differentiationIGI
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityIDA
GO:0060580ventral spinal cord interneuron fate determinationIMP
cellular_component
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0044424intracellular partIDA
molecular_function
GO:0001159core promoter proximal region DNA bindingIDA
GO:0003677DNA bindingIEA
GO:0003682chromatin bindingIDA
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0003713transcription coactivator activityIDA
GO:0005515protein bindingIPI
GO:0008134transcription factor bindingIPI
GO:0043565sequence-specific DNA bindingIDA

Protein-protein interaction details for Nkx2-2 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Tlx3Two-hybridphysical20211142