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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Nkx2-5 (
Mus musculus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
IDA
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
IGI
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
ISO
GO:0001570
vasculogenesis
IMP
GO:0001947
heart looping
IMP
GO:0003007
heart morphogenesis
IMP
GO:0003148
outflow tract septum morphogenesis
ISO
GO:0003151
outflow tract morphogenesis
IGI
GO:0003151
outflow tract morphogenesis
IMP
GO:0003161
cardiac conduction system development
ISO
GO:0003162
atrioventricular node development
IMP
GO:0003166
bundle of His development
IGI
GO:0003168
cardiac Purkinje fiber cell differentiation
IMP
GO:0003208
cardiac ventricle morphogenesis
IMP
GO:0003211
cardiac ventricle formation
IGI
GO:0003221
right ventricular cardiac muscle tissue morphogenesis
ISO
GO:0003222
ventricular trabecular myocardium morphogenesis
IMP
GO:0003278
apoptosis involved in heart morphogenesis
IMP
GO:0003285
septum secundum development
ISO
GO:0003342
proepicardium development
IMP
GO:0003350
pulmonary myocardium development
IMP
GO:0006351
transcription, DNA-dependent
ISO
GO:0006355
regulation of transcription, DNA-dependent
IEA
GO:0006357
regulation of transcription from RNA polymerase II promoter
IDA
GO:0007275
multicellular organismal development
IEA
GO:0007492
endoderm development
TAS
GO:0007507
heart development
IGI
GO:0007507
heart development
IMP
GO:0007512
adult heart development
IMP
GO:0007512
adult heart development
ISO
GO:0008284
positive regulation of cell proliferation
IGI
GO:0010628
positive regulation of gene expression
IDA
GO:0010667
negative regulation of cardiac muscle cell apoptosis
IMP
GO:0010667
negative regulation of cardiac muscle cell apoptosis
ISO
GO:0010735
positive regulation of transcription via serum response element binding
IDA
GO:0010765
positive regulation of sodium ion transport
IMP
GO:0010832
negative regulation of myotube differentiation
ISO
GO:0030097
hemopoiesis
IMP
GO:0030154
cell differentiation
IGI
GO:0030509
BMP signaling pathway
IDA
GO:0030878
thyroid gland development
IMP
GO:0030878
thyroid gland development
ISO
GO:0035050
embryonic heart tube development
IGI
GO:0043066
negative regulation of apoptosis
IGI
GO:0043586
tongue development
TAS
GO:0045214
sarcomere organization
IGI
GO:0045666
positive regulation of neuron differentiation
ISO
GO:0045823
positive regulation of heart contraction
IMP
GO:0045885
positive regulation of survival gene product expression
ISO
GO:0045893
positive regulation of transcription, DNA-dependent
IDA
GO:0045893
positive regulation of transcription, DNA-dependent
ISO
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IDA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IGI
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IMP
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISO
GO:0048536
spleen development
TAS
GO:0048738
cardiac muscle tissue development
IMP
GO:0051891
positive regulation of cardioblast differentiation
IMP
GO:0051929
positive regulation of calcium ion transport via voltage-gated calcium channel activity
IMP
GO:0055005
ventricular cardiac myofibril development
IMP
GO:0055007
cardiac muscle cell differentiation
IDA
GO:0055007
cardiac muscle cell differentiation
IGI
GO:0055007
cardiac muscle cell differentiation
IMP
GO:0055007
cardiac muscle cell differentiation
TAS
GO:0055008
cardiac muscle tissue morphogenesis
ISO
GO:0055014
atrial cardiac muscle cell development
TAS
GO:0055015
ventricular cardiac muscle cell development
TAS
GO:0055117
regulation of cardiac muscle contraction
IMP
GO:0060037
pharyngeal system development
IGI
GO:0060043
regulation of cardiac muscle cell proliferation
IDA
GO:0060048
cardiac muscle contraction
IMP
GO:0060070
canonical Wnt receptor signaling pathway
IDA
GO:0060261
positive regulation of transcription initiation from RNA polymerase II promoter
IDA
GO:0060347
heart trabecula formation
IMP
GO:0060412
ventricular septum morphogenesis
ISO
GO:0060413
atrial septum morphogenesis
ISO
GO:0060928
atrioventricular node cell development
IMP
GO:0060929
atrioventricular node cell fate commitment
IMP
GO:0060971
embryonic heart tube left/right pattern formation
IMP
GO:0072358
cardiovascular system development
IGI
GO:0090090
negative regulation of canonical Wnt receptor signaling pathway
IDA
cellular_component
GO:0005634
nucleus
IDA
GO:0005634
nucleus
ISO
GO:0005667
transcription factor complex
IDA
GO:0005667
transcription factor complex
IPI
GO:0005737
cytoplasm
IDA
molecular_function
GO:0003677
DNA binding
IDA
GO:0003677
DNA binding
ISO
GO:0003682
chromatin binding
IDA
GO:0003682
chromatin binding
ISO
GO:0003700
sequence-specific DNA binding transcription factor activity
IDA
GO:0003700
sequence-specific DNA binding transcription factor activity
ISO
GO:0003705
sequence-specific distal enhancer binding RNA polymerase II transcription factor activity
IDA
GO:0005515
protein binding
IPI
GO:0008134
transcription factor binding
ISO
GO:0010736
serum response element binding
IDA
GO:0042803
protein homodimerization activity
IDA
GO:0042803
protein homodimerization activity
ISO
GO:0043565
sequence-specific DNA binding
ISO
GO:0044212
transcription regulatory region DNA binding
ISO
GO:0046982
protein heterodimerization activity
IPI
Protein-protein interaction details for Nkx2-5 (
Mus musculus
)
(Information is obtained from BioGRID)
Interacting mouse protein
Experiment
Type
PubMed ID
Foxh1
Two-hybrid
physical
20211142
Smarca4
Affinity Capture-Western
physical
15525990