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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Nkx2-5 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterIDA
GO:0000122negative regulation of transcription from RNA polymerase II promoterIGI
GO:0000122negative regulation of transcription from RNA polymerase II promoterISO
GO:0001570vasculogenesisIMP
GO:0001947heart loopingIMP
GO:0003007heart morphogenesisIMP
GO:0003148outflow tract septum morphogenesisISO
GO:0003151outflow tract morphogenesisIGI
GO:0003151outflow tract morphogenesisIMP
GO:0003161cardiac conduction system developmentISO
GO:0003162atrioventricular node developmentIMP
GO:0003166bundle of His developmentIGI
GO:0003168cardiac Purkinje fiber cell differentiationIMP
GO:0003208cardiac ventricle morphogenesisIMP
GO:0003211cardiac ventricle formationIGI
GO:0003221right ventricular cardiac muscle tissue morphogenesisISO
GO:0003222ventricular trabecular myocardium morphogenesisIMP
GO:0003278apoptosis involved in heart morphogenesisIMP
GO:0003285septum secundum developmentISO
GO:0003342proepicardium developmentIMP
GO:0003350pulmonary myocardium developmentIMP
GO:0006351transcription, DNA-dependentISO
GO:0006355regulation of transcription, DNA-dependentIEA
GO:0006357regulation of transcription from RNA polymerase II promoterIDA
GO:0007275multicellular organismal developmentIEA
GO:0007492endoderm developmentTAS
GO:0007507heart developmentIGI
GO:0007507heart developmentIMP
GO:0007512adult heart developmentIMP
GO:0007512adult heart developmentISO
GO:0008284positive regulation of cell proliferationIGI
GO:0010628positive regulation of gene expressionIDA
GO:0010667negative regulation of cardiac muscle cell apoptosisIMP
GO:0010667negative regulation of cardiac muscle cell apoptosisISO
GO:0010735positive regulation of transcription via serum response element bindingIDA
GO:0010765positive regulation of sodium ion transportIMP
GO:0010832negative regulation of myotube differentiationISO
GO:0030097hemopoiesisIMP
GO:0030154cell differentiationIGI
GO:0030509BMP signaling pathwayIDA
GO:0030878thyroid gland developmentIMP
GO:0030878thyroid gland developmentISO
GO:0035050embryonic heart tube developmentIGI
GO:0043066negative regulation of apoptosisIGI
GO:0043586tongue developmentTAS
GO:0045214sarcomere organizationIGI
GO:0045666positive regulation of neuron differentiationISO
GO:0045823positive regulation of heart contractionIMP
GO:0045885positive regulation of survival gene product expressionISO
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentISO
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIGI
GO:0045944positive regulation of transcription from RNA polymerase II promoterIMP
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0048536spleen developmentTAS
GO:0048738cardiac muscle tissue developmentIMP
GO:0051891positive regulation of cardioblast differentiationIMP
GO:0051929positive regulation of calcium ion transport via voltage-gated calcium channel activityIMP
GO:0055005ventricular cardiac myofibril developmentIMP
GO:0055007cardiac muscle cell differentiationIDA
GO:0055007cardiac muscle cell differentiationIGI
GO:0055007cardiac muscle cell differentiationIMP
GO:0055007cardiac muscle cell differentiationTAS
GO:0055008cardiac muscle tissue morphogenesisISO
GO:0055014atrial cardiac muscle cell developmentTAS
GO:0055015ventricular cardiac muscle cell developmentTAS
GO:0055117regulation of cardiac muscle contractionIMP
GO:0060037pharyngeal system developmentIGI
GO:0060043regulation of cardiac muscle cell proliferationIDA
GO:0060048cardiac muscle contractionIMP
GO:0060070canonical Wnt receptor signaling pathwayIDA
GO:0060261positive regulation of transcription initiation from RNA polymerase II promoterIDA
GO:0060347heart trabecula formationIMP
GO:0060412ventricular septum morphogenesisISO
GO:0060413atrial septum morphogenesisISO
GO:0060928atrioventricular node cell developmentIMP
GO:0060929atrioventricular node cell fate commitmentIMP
GO:0060971embryonic heart tube left/right pattern formationIMP
GO:0072358cardiovascular system developmentIGI
GO:0090090negative regulation of canonical Wnt receptor signaling pathwayIDA
cellular_component
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0005667transcription factor complexIDA
GO:0005667transcription factor complexIPI
GO:0005737cytoplasmIDA
molecular_function
GO:0003677DNA bindingIDA
GO:0003677DNA bindingISO
GO:0003682chromatin bindingIDA
GO:0003682chromatin bindingISO
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0003700sequence-specific DNA binding transcription factor activityISO
GO:0003705sequence-specific distal enhancer binding RNA polymerase II transcription factor activityIDA
GO:0005515protein bindingIPI
GO:0008134transcription factor bindingISO
GO:0010736serum response element bindingIDA
GO:0042803protein homodimerization activityIDA
GO:0042803protein homodimerization activityISO
GO:0043565sequence-specific DNA bindingISO
GO:0044212transcription regulatory region DNA bindingISO
GO:0046982protein heterodimerization activityIPI

Protein-protein interaction details for Nkx2-5 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Foxh1Two-hybridphysical20211142
Smarca4Affinity Capture-Westernphysical15525990