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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Notch1 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001701in utero embryonic developmentIMP
GO:0001708cell fate specificationIMP
GO:0001837epithelial to mesenchymal transitionIMP
GO:0001889liver developmentIMP
GO:0002040sprouting angiogenesisIMP
GO:0002052positive regulation of neuroblast proliferationISO
GO:0003180aortic valve morphogenesisISO
GO:0003264regulation of cardioblast proliferationISO
GO:0006351transcription, DNA-dependentISO
GO:0006357regulation of transcription from RNA polymerase II promoterIGI
GO:0007219Notch signaling pathwayIMP
GO:0007219Notch signaling pathwayISO
GO:0007221positive regulation of transcription of Notch receptor targetIGI
GO:0007221positive regulation of transcription of Notch receptor targetISO
GO:0007283spermatogenesisISO
GO:0007368determination of left/right symmetryIMP
GO:0007386compartment pattern specificationIMP
GO:0007409axonogenesisIDA
GO:0007409axonogenesisIMP
GO:0007440foregut morphogenesisIMP
GO:0007492endoderm developmentIMP
GO:0007507heart developmentIMP
GO:0007507heart developmentISO
GO:0008284positive regulation of cell proliferationIGI
GO:0008284positive regulation of cell proliferationISO
GO:0008544epidermis developmentIGI
GO:0009790embryo developmentISO
GO:0009912auditory receptor cell fate commitmentIMP
GO:0010001glial cell differentiationIMP
GO:0010468regulation of gene expressionIMP
GO:0010718positive regulation of epithelial to mesenchymal transitionISO
GO:0010812negative regulation of cell-substrate adhesionISO
GO:0014807regulation of somitogenesisIMP
GO:0021915neural tube developmentIMP
GO:0030154cell differentiationIMP
GO:0030182neuron differentiationIMP
GO:0030216keratinocyte differentiationIMP
GO:0030324lung developmentIMP
GO:0030326embryonic limb morphogenesisIGI
GO:0030900forebrain developmentIGI
GO:0030900forebrain developmentIMP
GO:0031069hair follicle morphogenesisIMP
GO:0035116embryonic hindlimb morphogenesisIMP
GO:0042127regulation of cell proliferationISO
GO:0042640anagenIMP
GO:0043065positive regulation of apoptosisIDA
GO:0043065positive regulation of apoptosisIGI
GO:0043066negative regulation of apoptosisIMP
GO:0045165cell fate commitmentIMP
GO:0045596negative regulation of cell differentiationIMP
GO:0045603positive regulation of endothelial cell differentiationISO
GO:0045618positive regulation of keratinocyte differentiationIDA
GO:0045618positive regulation of keratinocyte differentiationIGI
GO:0045662negative regulation of myoblast differentiationISO
GO:0045665negative regulation of neuron differentiationIGI
GO:0045665negative regulation of neuron differentiationIMP
GO:0045665negative regulation of neuron differentiationISO
GO:0045687positive regulation of glial cell differentiationISO
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIGI
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0045955negative regulation of calcium ion-dependent exocytosisIMP
GO:0046533negative regulation of photoreceptor cell differentiationIMP
GO:0048103somatic stem cell divisionIDA
GO:0048103somatic stem cell divisionIGI
GO:0048663neuron fate commitmentIGI
GO:0048708astrocyte differentiationISO
GO:0048754branching morphogenesis of a tubeIMP
GO:0050678regulation of epithelial cell proliferationIMP
GO:0050679positive regulation of epithelial cell proliferationIGI
GO:0050767regulation of neurogenesisIMP
GO:0060528secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus developmentIMP
GO:0060548negative regulation of cell deathIMP
GO:0060740prostate gland epithelium morphogenesisIMP
GO:0060768regulation of epithelial cell proliferation involved in prostate gland developmentIMP
GO:2000737negative regulation of stem cell differentiationISO
cellular_component
GO:0001669acrosomal vesicleISO
GO:0002193MAML1-RBP-Jkappa- ICN1 complexISO
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0005737cytoplasmIDA
GO:0005794Golgi apparatusISO
GO:0005886plasma membraneIDA
GO:0005886plasma membraneISO
GO:0016021integral to membraneIEA
molecular_function
GO:0003682chromatin bindingIDA
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0004872receptor activityIEA
GO:0031490chromatin DNA bindingIDA
GO:0043565sequence-specific DNA bindingIDA

Protein-protein interaction details for Notch1 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Kat2bTwo-hybridphysical10747963
Kat2aTwo-hybridphysical10747963
Wdr12Reconstituted Complexphysical11827460
Smarcd3Affinity Capture-Westernphysical17210915
RbpjAffinity Capture-Westernphysical17210915
Dll1Reconstituted Complexphysical21985982
NumbAffinity Capture-Westernphysical20844536
NumbAffinity Capture-Westernphysical20844536
UbcAffinity Capture-Westernphysical20844536