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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for DRD3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA GO:0001963 synaptic transmission, dopaminergic IEA GO:0002016 regulation of blood volume by renin-angiotensin IEA GO:0002031 G-protein coupled receptor internalization IDA GO:0006874 cellular calcium ion homeostasis IDA GO:0007186 G-protein coupled receptor protein signaling pathway IDA GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway IDA GO:0007194 negative regulation of adenylate cyclase activity IDA GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway IDA GO:0007611 learning or memory NAS GO:0007612 learning NAS GO:0007626 locomotory behavior ISS GO:0008284 positive regulation of cell proliferation IEA GO:0008542 visual learning ISS GO:0014059 regulation of dopamine secretion ISS GO:0019216 regulation of lipid metabolic process IEA GO:0030814 regulation of cAMP metabolic process IDA GO:0032416 negative regulation of sodium:hydrogen antiporter activity IEA GO:0032922 circadian regulation of gene expression ISS GO:0034776 response to histamine IDA GO:0035176 social behavior NAS GO:0040012 regulation of locomotion IEA GO:0040014 regulation of multicellular organism growth IEA GO:0042220 response to cocaine IEP GO:0042417 dopamine metabolic process IC GO:0042493 response to drug ISS GO:0043278 response to morphine ISS GO:0045187 regulation of circadian sleep/wake cycle, sleep IEA GO:0045471 response to ethanol ISS GO:0045776 negative regulation of blood pressure ISS GO:0045840 positive regulation of mitosis ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0046717 acid secretion ISS GO:0048148 behavioral response to cocaine IEP GO:0048148 behavioral response to cocaine ISS GO:0048715 negative regulation of oligodendrocyte differentiation ISS GO:0050482 arachidonic acid secretion IDA GO:0050709 negative regulation of protein secretion IDA GO:0050883 musculoskeletal movement, spinal reflex action ISS GO:0051584 regulation of dopamine uptake IC GO:0051898 negative regulation of protein kinase B signaling cascade ISS GO:0060134 prepulse inhibition IMP GO:0060161 positive regulation of dopamine receptor signaling pathway ISS cellular_component GO:0005624 membrane fraction IEA GO:0005886 plasma membrane IDA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane IC GO:0005887 integral to plasma membrane IDA GO:0016021 integral to membrane IEA GO:0030139 endocytic vesicle IEA GO:0042995 cell projection IEA GO:0045177 apical part of cell IEA molecular_function GO:0001591 dopamine receptor activity, coupled via Gi/Go ISS GO:0001592 dopamine D3 receptor activity IDA GO:0004871 signal transducer activity IEA GO:0004872 receptor activity IEA GO:0004930 G-protein coupled receptor activity IEA GO:0004952 dopamine receptor activity IEA GO:0005515 protein binding IPI GO:0008144 drug binding IDA GO:0008144 drug binding ISS GO:0019904 protein domain specific binding IEA

Protein-protein interaction details for DRD3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID FLNA Two-hybrid physical 11911837 CLIC6 Two-hybrid physical 14499480 MPDZ Two-hybrid physical 14499480 GIPC1 Two-hybrid physical 14499480 RDX Two-hybrid physical 14499480 CLIC6 Reconstituted Complex physical 14499480 NCS1 Affinity Capture-Western physical 12351722 EPB41L1 Reconstituted Complex physical 12181426 EPB41L1 Affinity Capture-Western physical 12181426 EPB41L1 Two-hybrid physical 12181426 GRB2 Reconstituted Complex physical 11384839