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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for JAG1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001525angiogenesisNAS
GO:0001709cell fate determinationNAS
GO:0002011morphogenesis of an epithelial sheetIEA
GO:0007154cell communicationIEA
GO:0007219Notch signaling pathwayIMP
GO:0007219Notch signaling pathwayNAS
GO:0007219Notch signaling pathwayTAS
GO:0007220Notch receptor processingTAS
GO:0007275multicellular organismal developmentNAS
GO:0007399nervous system developmentNAS
GO:0009887organ morphogenesisIEA
GO:0030097hemopoiesisNAS
GO:0030216keratinocyte differentiationNAS
GO:0030334regulation of cell migrationNAS
GO:0032495response to muramyl dipeptideIEA
GO:0042127regulation of cell proliferationIEA
GO:0042127regulation of cell proliferationNAS
GO:0042491auditory receptor cell differentiationIEA
GO:0045445myoblast differentiationNAS
GO:0045446endothelial cell differentiationNAS
GO:0045599negative regulation of fat cell differentiationIEA
GO:0045639positive regulation of myeloid cell differentiationIEA
GO:0045747positive regulation of Notch signaling pathwayIEA
GO:0048839inner ear developmentIEA
GO:0097150neuronal stem cell maintenanceIEP
GO:2000737negative regulation of stem cell differentiationIMP
cellular_component
GO:0005576extracellular regionNAS
GO:0005886plasma membraneIEA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneNAS
GO:0016020membraneTAS
molecular_function
GO:0005112Notch bindingIEA
GO:0005112Notch bindingNAS
GO:0005198structural molecule activityNAS
GO:0005509calcium ion bindingIEA
GO:0005509calcium ion bindingNAS
GO:0008083growth factor activityNAS

Protein-protein interaction details for JAG1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
NOTCH2Affinity Capture-Westernphysical11346656
NOTCH1Reconstituted Complexphysical11006133
NOTCH3Reconstituted Complexphysical11006133
MLLT4Two-hybridphysical9707552
NOTCH2Reconstituted Complexphysical10551863
NOTCH2Affinity Capture-Westernphysical10551863
NOTCH2Affinity Capture-Westernphysical10958687
NOTCH2Reconstituted Complexphysical10958687
NOTCH1Co-localizationphysical20720151
MIB1Affinity Capture-Westernphysical20720151
UBCAffinity Capture-Westernphysical20720151
HGSAffinity Capture-Westernphysical20720151
NEURLBiochemical Activityphysical18077452
NEURLAffinity Capture-Westernphysical18077452
UBCAffinity Capture-Westernphysical18077452