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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HBEGF (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0007165signal transductionTAS
GO:0007173epidermal growth factor receptor signaling pathwayIMP
GO:0007517muscle organ developmentTAS
GO:0008016regulation of heart contractionIEA
GO:0030307positive regulation of cell growthIEA
GO:0030335positive regulation of cell migrationIMP
GO:0035313wound healing, spreading of epidermal cellsIEA
GO:0048661positive regulation of smooth muscle cell proliferationIEA
GO:0051545negative regulation of elastin biosynthetic processIEA
GO:0051549positive regulation of keratinocyte migrationIEA
GO:0051897positive regulation of protein kinase B signaling cascadeIMP
GO:0090303positive regulation of wound healingIMP
cellular_component
GO:0005576extracellular regionIEA
GO:0005615extracellular spaceIDA
GO:0005615extracellular spaceISS
GO:0005615extracellular spaceTAS
GO:0005886plasma membraneIEA
GO:0005887integral to plasma membraneISS
GO:0005887integral to plasma membraneTAS
GO:0009986cell surfaceIDA
GO:0009986cell surfaceNAS
molecular_function
GO:0004872receptor activityIEA
GO:0005154epidermal growth factor receptor bindingIEA
GO:0008083growth factor activityIEA
GO:0008201heparin bindingIMP
GO:0043499eukaryotic cell surface bindingIDA

Protein-protein interaction details for HBEGF (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
ZBTB16Two-hybridphysical14597771
ZBTB16Reconstituted Complexphysical15219838
ZBTB16Affinity Capture-Westernphysical14597771
ZBTB16Reconstituted Complexphysical14597771
EGFRAffinity Capture-Westernphysical12725245
MMP7Affinity Capture-Westernphysical11825873
NRD1Affinity Capture-Westernphysical11432822
NRD1Reconstituted Complexphysical11432822
BAG1Two-hybridphysical11340068
BAG1Affinity Capture-Westernphysical11340068
CD82Affinity Capture-Westernphysical10749879
CD44Reconstituted Complexphysical7532176