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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for HBEGF (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0007165
signal transduction
TAS
GO:0007173
epidermal growth factor receptor signaling pathway
IMP
GO:0007517
muscle organ development
TAS
GO:0008016
regulation of heart contraction
IEA
GO:0030307
positive regulation of cell growth
IEA
GO:0030335
positive regulation of cell migration
IMP
GO:0035313
wound healing, spreading of epidermal cells
IEA
GO:0048661
positive regulation of smooth muscle cell proliferation
IEA
GO:0051545
negative regulation of elastin biosynthetic process
IEA
GO:0051549
positive regulation of keratinocyte migration
IEA
GO:0051897
positive regulation of protein kinase B signaling cascade
IMP
GO:0090303
positive regulation of wound healing
IMP
cellular_component
GO:0005576
extracellular region
IEA
GO:0005615
extracellular space
IDA
GO:0005615
extracellular space
ISS
GO:0005615
extracellular space
TAS
GO:0005886
plasma membrane
IEA
GO:0005887
integral to plasma membrane
ISS
GO:0005887
integral to plasma membrane
TAS
GO:0009986
cell surface
IDA
GO:0009986
cell surface
NAS
molecular_function
GO:0004872
receptor activity
IEA
GO:0005154
epidermal growth factor receptor binding
IEA
GO:0008083
growth factor activity
IEA
GO:0008201
heparin binding
IMP
GO:0043499
eukaryotic cell surface binding
IDA
Protein-protein interaction details for HBEGF (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
ZBTB16
Two-hybrid
physical
14597771
ZBTB16
Reconstituted Complex
physical
15219838
ZBTB16
Affinity Capture-Western
physical
14597771
ZBTB16
Reconstituted Complex
physical
14597771
EGFR
Affinity Capture-Western
physical
12725245
MMP7
Affinity Capture-Western
physical
11825873
NRD1
Affinity Capture-Western
physical
11432822
NRD1
Reconstituted Complex
physical
11432822
BAG1
Two-hybrid
physical
11340068
BAG1
Affinity Capture-Western
physical
11340068
CD82
Affinity Capture-Western
physical
10749879
CD44
Reconstituted Complex
physical
7532176