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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Pik3r1 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001934positive regulation of protein phosphorylationISO
GO:0001953negative regulation of cell-matrix adhesionIGI
GO:0006006glucose metabolic processISO
GO:0006468protein phosphorylationIDA
GO:0007165signal transductionIEA
GO:0008286insulin receptor signaling pathwayISO
GO:0010459negative regulation of heart rateISO
GO:0010628positive regulation of gene expressionISO
GO:0014065phosphatidylinositol 3-kinase cascadeISO
GO:0016310phosphorylationIEA
GO:0022408negative regulation of cell-cell adhesionISO
GO:0030183B cell differentiationIMP
GO:0030335positive regulation of cell migrationIGI
GO:0030335positive regulation of cell migrationISO
GO:0032868response to insulin stimulusISO
GO:0034644cellular response to UVIGI
GO:0034644cellular response to UVIMP
GO:0043065positive regulation of apoptosisIGI
GO:0043065positive regulation of apoptosisIMP
GO:0043066negative regulation of apoptosisIDA
GO:0043066negative regulation of apoptosisIGI
GO:0043551regulation of phosphatidylinositol 3-kinase activityISO
GO:0045663positive regulation of myoblast differentiationISO
GO:0045671negative regulation of osteoclast differentiationIGI
GO:0045768positive regulation of anti-apoptosisISO
GO:0045776negative regulation of blood pressureISO
GO:0045861negative regulation of proteolysisISO
GO:0045944positive regulation of transcription from RNA polymerase II promoterIMP
GO:0046854phosphatidylinositol phosphorylationTAS
GO:0048009insulin-like growth factor receptor signaling pathwayISO
GO:0048662negative regulation of smooth muscle cell proliferationISO
GO:0051384response to glucocorticoid stimulusISO
GO:0051531NFAT protein import into nucleusIMP
GO:0051591response to cAMPISO
GO:0060396growth hormone receptor signaling pathwayISO
cellular_component
GO:0005622intracellularIEA
GO:0005624membrane fractionISO
GO:0005625soluble fractionISO
GO:0005634nucleusISO
GO:0005737cytoplasmIDA
GO:0005829cytosolIDA
GO:0005886plasma membraneISO
GO:0005942phosphatidylinositol 3-kinase complexISO
GO:0005942phosphatidylinositol 3-kinase complexTAS
GO:0016020membraneIDA
GO:0019717synaptosomeISO
GO:0043234protein complexISO
molecular_function
GO:0005102receptor bindingISO
GO:0005158insulin receptor bindingISO
GO:0005159insulin-like growth factor receptor bindingISO
GO:0005161platelet-derived growth factor receptor bindingISO
GO:0005515protein bindingIPI
GO:0005516calmodulin bindingISO
GO:0008022protein C-terminus bindingISO
GO:0016301kinase activityIEA
GO:00163031-phosphatidylinositol-3-kinase activityISO
GO:00163031-phosphatidylinositol-3-kinase activityTAS
GO:0019901protein kinase bindingISO
GO:0019903protein phosphatase bindingISO
GO:0019904protein domain specific bindingISO
GO:0030331estrogen receptor bindingISO
GO:0030971receptor tyrosine kinase bindingISO
GO:0031625ubiquitin protein ligase bindingISO
GO:0035014phosphatidylinositol 3-kinase regulator activityIEA
GO:0043125ErbB-3 class receptor bindingISO
GO:0043548phosphatidylinositol 3-kinase bindingISO
GO:0043559insulin bindingISO
GO:0043560insulin receptor substrate bindingIPI
GO:0043560insulin receptor substrate bindingISO
GO:00469351-phosphatidylinositol-3-kinase regulator activityISO
GO:0051117ATPase bindingISO
GO:0051219phosphoprotein bindingISO

Protein-protein interaction details for Pik3r1 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
CblAffinity Capture-Westernphysical9174058
Grb2Affinity Capture-Westernphysical9174058
Grb2Reconstituted Complexphysical9174058
TekTwo-hybridphysical10521483
TekReconstituted Complexphysical10521483
TekAffinity Capture-Westernphysical10521483
Irs1Affinity Capture-Westernphysical15380067
Irs2Affinity Capture-Westernphysical15380067
Cd19Affinity Capture-Westernphysical11163197