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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Pik3r1 (
Mus musculus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001934
positive regulation of protein phosphorylation
ISO
GO:0001953
negative regulation of cell-matrix adhesion
IGI
GO:0006006
glucose metabolic process
ISO
GO:0006468
protein phosphorylation
IDA
GO:0007165
signal transduction
IEA
GO:0008286
insulin receptor signaling pathway
ISO
GO:0010459
negative regulation of heart rate
ISO
GO:0010628
positive regulation of gene expression
ISO
GO:0014065
phosphatidylinositol 3-kinase cascade
ISO
GO:0016310
phosphorylation
IEA
GO:0022408
negative regulation of cell-cell adhesion
ISO
GO:0030183
B cell differentiation
IMP
GO:0030335
positive regulation of cell migration
IGI
GO:0030335
positive regulation of cell migration
ISO
GO:0032868
response to insulin stimulus
ISO
GO:0034644
cellular response to UV
IGI
GO:0034644
cellular response to UV
IMP
GO:0043065
positive regulation of apoptosis
IGI
GO:0043065
positive regulation of apoptosis
IMP
GO:0043066
negative regulation of apoptosis
IDA
GO:0043066
negative regulation of apoptosis
IGI
GO:0043551
regulation of phosphatidylinositol 3-kinase activity
ISO
GO:0045663
positive regulation of myoblast differentiation
ISO
GO:0045671
negative regulation of osteoclast differentiation
IGI
GO:0045768
positive regulation of anti-apoptosis
ISO
GO:0045776
negative regulation of blood pressure
ISO
GO:0045861
negative regulation of proteolysis
ISO
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IMP
GO:0046854
phosphatidylinositol phosphorylation
TAS
GO:0048009
insulin-like growth factor receptor signaling pathway
ISO
GO:0048662
negative regulation of smooth muscle cell proliferation
ISO
GO:0051384
response to glucocorticoid stimulus
ISO
GO:0051531
NFAT protein import into nucleus
IMP
GO:0051591
response to cAMP
ISO
GO:0060396
growth hormone receptor signaling pathway
ISO
cellular_component
GO:0005622
intracellular
IEA
GO:0005624
membrane fraction
ISO
GO:0005625
soluble fraction
ISO
GO:0005634
nucleus
ISO
GO:0005737
cytoplasm
IDA
GO:0005829
cytosol
IDA
GO:0005886
plasma membrane
ISO
GO:0005942
phosphatidylinositol 3-kinase complex
ISO
GO:0005942
phosphatidylinositol 3-kinase complex
TAS
GO:0016020
membrane
IDA
GO:0019717
synaptosome
ISO
GO:0043234
protein complex
ISO
molecular_function
GO:0005102
receptor binding
ISO
GO:0005158
insulin receptor binding
ISO
GO:0005159
insulin-like growth factor receptor binding
ISO
GO:0005161
platelet-derived growth factor receptor binding
ISO
GO:0005515
protein binding
IPI
GO:0005516
calmodulin binding
ISO
GO:0008022
protein C-terminus binding
ISO
GO:0016301
kinase activity
IEA
GO:0016303
1-phosphatidylinositol-3-kinase activity
ISO
GO:0016303
1-phosphatidylinositol-3-kinase activity
TAS
GO:0019901
protein kinase binding
ISO
GO:0019903
protein phosphatase binding
ISO
GO:0019904
protein domain specific binding
ISO
GO:0030331
estrogen receptor binding
ISO
GO:0030971
receptor tyrosine kinase binding
ISO
GO:0031625
ubiquitin protein ligase binding
ISO
GO:0035014
phosphatidylinositol 3-kinase regulator activity
IEA
GO:0043125
ErbB-3 class receptor binding
ISO
GO:0043548
phosphatidylinositol 3-kinase binding
ISO
GO:0043559
insulin binding
ISO
GO:0043560
insulin receptor substrate binding
IPI
GO:0043560
insulin receptor substrate binding
ISO
GO:0046935
1-phosphatidylinositol-3-kinase regulator activity
ISO
GO:0051117
ATPase binding
ISO
GO:0051219
phosphoprotein binding
ISO
Protein-protein interaction details for Pik3r1 (
Mus musculus
)
(Information is obtained from BioGRID)
Interacting mouse protein
Experiment
Type
PubMed ID
Cbl
Affinity Capture-Western
physical
9174058
Grb2
Affinity Capture-Western
physical
9174058
Grb2
Reconstituted Complex
physical
9174058
Tek
Two-hybrid
physical
10521483
Tek
Reconstituted Complex
physical
10521483
Tek
Affinity Capture-Western
physical
10521483
Irs1
Affinity Capture-Western
physical
15380067
Irs2
Affinity Capture-Western
physical
15380067
Cd19
Affinity Capture-Western
physical
11163197