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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Plk1 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000236mitotic prometaphaseISO
GO:0006468protein phosphorylationIEA
GO:0006468protein phosphorylationISO
GO:0007049cell cycleIEA
GO:0007067mitosisISO
GO:0007346regulation of mitotic cell cycleISO
GO:0010800positive regulation of peptidyl-threonine phosphorylationISO
GO:0016310phosphorylationIEA
GO:0016567protein ubiquitinationISO
GO:0018105peptidyl-serine phosphorylationISO
GO:0031572G2/M transition DNA damage checkpointISO
GO:0031648protein destabilizationISO
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic processISO
GO:0040038polar body extrusion after meiotic divisionsISO
GO:0043393regulation of protein bindingISO
GO:0045736negative regulation of cyclin-dependent protein kinase activityISO
GO:0045862positive regulation of proteolysisISO
GO:0051301cell divisionIEA
GO:0051443positive regulation of ubiquitin-protein ligase activityISO
GO:0071168protein localization to chromatinISO
GO:0090007regulation of mitotic anaphaseISO
cellular_component
GO:0000775chromosome, centromeric regionIEA
GO:0000776kinetochoreISO
GO:0000922spindle poleISO
GO:0000942condensed nuclear chromosome outer kinetochoreISO
GO:0005634nucleusISO
GO:0005694chromosomeIEA
GO:0005737cytoplasmISO
GO:0005813centrosomeISO
GO:0005856cytoskeletonIEA
GO:0005876spindle microtubuleISO
GO:0030496midbodyISO
GO:0051233spindle midzoneISO
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004672protein kinase activityISO
GO:0004674protein serine/threonine kinase activityISO
GO:0005524ATP bindingIEA
GO:0010997anaphase-promoting complex bindingISO
GO:0016301kinase activityIEA
GO:0016740transferase activityIEA
GO:0016772transferase activity, transferring phosphorus-containing groupsIEA
GO:0019901protein kinase bindingISO
GO:0042801polo kinase kinase activityISO

Protein-protein interaction details for Plk1 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
UbcAffinity Capture-Westernphysical9826531
Bat1aTwo-hybridphysical21637952
Bat1aAffinity Capture-Westernphysical21637952
Bat1aBiochemical Activityphysical21637952
Bat1aReconstituted Complexphysical21637952