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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ECT2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000902 cell morphogenesis IEA GO:0006915 apoptosis TAS GO:0007165 signal transduction IMP GO:0007264 small GTPase mediated signal transduction TAS GO:0008624 induction of apoptosis by extracellular signals TAS GO:0032147 activation of protein kinase activity IDA GO:0032321 positive regulation of Rho GTPase activity IDA GO:0032321 positive regulation of Rho GTPase activity IMP GO:0032862 activation of Rho GTPase activity IDA GO:0032863 activation of Rac GTPase activity IMP GO:0033205 cell cycle cytokinesis IMP GO:0035023 regulation of Rho protein signal transduction IEA GO:0035556 intracellular signal transduction IEA GO:0042307 positive regulation of protein import into nucleus ISS GO:0043065 positive regulation of apoptosis IDA GO:0043089 positive regulation of Cdc42 GTPase activity IDA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IMP GO:0045666 positive regulation of neuron differentiation ISS GO:0045859 regulation of protein kinase activity IDA GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0051056 regulation of small GTPase mediated signal transduction TAS GO:0051260 protein homooligomerization IDA GO:0051988 regulation of attachment of spindle microtubules to kinetochore IMP GO:0070301 cellular response to hydrogen peroxide IDA GO:0070830 tight junction assembly IMP GO:0071277 cellular response to calcium ion IDA GO:0071479 cellular response to ionizing radiation IDA GO:0071777 positive regulation of cell cycle cytokinesis IDA GO:0071777 positive regulation of cell cycle cytokinesis IMP cellular_component GO:0005622 intracellular IEA GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS GO:0005911 cell-cell junction IDA GO:0005923 tight junction IDA GO:0030496 midbody IDA GO:0032154 cleavage furrow IDA GO:0072686 mitotic spindle IDA molecular_function GO:0004871 signal transducer activity IMP GO:0005085 guanyl-nucleotide exchange factor activity IEA GO:0005089 Rho guanyl-nucleotide exchange factor activity IDA GO:0005089 Rho guanyl-nucleotide exchange factor activity IEA GO:0005096 GTPase activator activity IMP GO:0005515 protein binding IPI GO:0017048 Rho GTPase binding IEA GO:0042803 protein homodimerization activity IDA

Protein-protein interaction details for ECT2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PARD6A Two-hybrid physical 15254234 KLHL20 Two-hybrid physical 14668487 PARD6A Affinity Capture-Western physical 15254234 PARD6A Affinity Capture-Western physical 15254234 PARD6A Reconstituted Complex physical 15254234 PRKCZ Affinity Capture-Western physical 15254234 PARD3 Affinity Capture-Western physical 15254234