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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NR0B1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA GO:0006694 steroid biosynthetic process IDA GO:0006950 response to stress IEA GO:0007283 spermatogenesis IEA GO:0008104 protein localization IDA GO:0008406 gonad development IMP GO:0008584 male gonad development IMP GO:0010033 response to organic substance IEA GO:0010467 gene expression TAS GO:0021854 hypothalamus development NAS GO:0021983 pituitary gland development NAS GO:0030238 male sex determination IEA GO:0030325 adrenal gland development IMP GO:0030522 intracellular receptor mediated signaling pathway NAS GO:0033144 negative regulation of steroid hormone receptor signaling pathway IDA GO:0033327 Leydig cell differentiation IEA GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor TAS GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity IMP GO:0043434 response to peptide hormone stimulus IEA GO:0045596 negative regulation of cell differentiation IEA GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045892 negative regulation of transcription, DNA-dependent IMP GO:0060008 Sertoli cell differentiation IEA cellular_component GO:0005624 membrane fraction IDA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IDA GO:0042788 polysomal ribosome IDA molecular_function GO:0003677 DNA binding IDA GO:0003690 double-stranded DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003706 ligand-regulated transcription factor activity IDA GO:0003707 steroid hormone receptor activity IEA GO:0003714 transcription corepressor activity IMP GO:0003723 RNA binding IDA GO:0004872 receptor activity IEA GO:0004879 ligand-dependent nuclear receptor activity NAS GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0019904 protein domain specific binding IPI GO:0032448 DNA hairpin binding IDA GO:0035258 steroid hormone receptor binding IPI GO:0042803 protein homodimerization activity IPI GO:0043565 sequence-specific DNA binding IDA GO:0050682 AF-2 domain binding IPI

Protein-protein interaction details for NR0B1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID NRIP1 Two-hybrid physical 11459805 NR5A1 Reconstituted Complex physical 11713202 SREBF1 Reconstituted Complex physical 11713202 SREBF1 Two-hybrid physical 11713202 NR5A1 Two-hybrid physical 11713202 COPS2 Two-hybrid physical 10713076 COPS2 Reconstituted Complex physical 10713076 AR Affinity Capture-Western physical 11875111 NRIP1 Reconstituted Complex physical 11459805 NR5A1 Reconstituted Complex physical 11459805 AR Affinity Capture-Western physical 12771131 PGR Reconstituted Complex physical 12771131 PGR Reconstituted Complex physical 12771131 PGR Affinity Capture-Western physical 12771131 POU5F1 Affinity Capture-Western physical 19528230 POU5F1 Affinity Capture-Western physical 19528230 POU5F1 Reconstituted Complex physical 19528230 POU5F1 Reconstituted Complex physical 19528230 SNW1 Two-hybrid physical 15604093 ESRRA Two-hybrid physical 15604093 SNW1 Two-hybrid physical 15604093 PPARG Two-hybrid physical 15604093 ESRRG Two-hybrid physical 15604093