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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for S1PR1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001525 angiogenesis IEA GO:0007155 cell adhesion TAS GO:0007186 G-protein coupled receptor protein signaling pathway TAS GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling pathway IEA GO:0007420 brain development IEA GO:0019226 transmission of nerve impulse IEA GO:0030155 regulation of cell adhesion IEA GO:0030182 neuron differentiation IEA GO:0030335 positive regulation of cell migration IEA GO:0032320 positive regulation of Ras GTPase activity IEA GO:0045446 endothelial cell differentiation IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0048661 positive regulation of smooth muscle cell proliferation IEA GO:0050927 positive regulation of positive chemotaxis IEA GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger IEA GO:0051497 negative regulation of stress fiber assembly IEA cellular_component GO:0005886 plasma membrane TAS GO:0009897 external side of plasma membrane IEA GO:0016021 integral to membrane IEA molecular_function GO:0001619 lysosphingolipid and lysophosphatidic acid receptor activity IEA GO:0004871 signal transducer activity IEA GO:0004872 receptor activity IEA GO:0004930 G-protein coupled receptor activity IEA GO:0046625 sphingolipid binding IEA

Protein-protein interaction details for S1PR1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HTR1A Affinity Capture-Western physical 11854302 HTR1A Affinity Capture-Western physical 11854302 HTR1D Affinity Capture-Western physical 11854302 CAV1 Affinity Capture-Western physical 10921915 PDGFRB Affinity Capture-Western physical 12480944 GNAI3 Affinity Capture-Western physical 8626678 GNAI1 Affinity Capture-Western physical 8626678 GNAI3 Reconstituted Complex physical 8626678 GNAI1 Reconstituted Complex physical 8626678 GNAI1 Two-hybrid physical 8626678 GNAI3 Two-hybrid physical 8626678 TRIP6 Affinity Capture-Western physical 19293149 UBC Affinity Capture-MS physical 21555855 UBC Affinity Capture-Western physical 21555855 WWP2 Affinity Capture-Western physical 21555855 WWP2 Affinity Capture-Western physical 21555855 WWP2 Affinity Capture-MS physical 21555855