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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for EDN1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterIDA
GO:0001516prostaglandin biosynthetic processIDA
GO:0001569patterning of blood vesselsIEA
GO:0001666response to hypoxiaIEA
GO:0001701in utero embryonic developmentIEA
GO:0001821histamine secretionIEA
GO:0003100regulation of systemic arterial blood pressure by endothelinIDA
GO:0006885regulation of pHIEA
GO:0007166cell surface receptor linked signaling pathwayIDA
GO:0007186G-protein coupled receptor protein signaling pathwayIDA
GO:0007204elevation of cytosolic calcium ion concentrationIDA
GO:0007205activation of protein kinase C activity by G-protein coupled receptor protein signaling pathwayIEA
GO:0007243intracellular protein kinase cascadeIEA
GO:0007267cell-cell signalingIDA
GO:0007507heart developmentIEA
GO:0007585respiratory gaseous exchangeIEA
GO:0007589body fluid secretionIEA
GO:0008217regulation of blood pressureIEA
GO:0008284positive regulation of cell proliferationIDA
GO:0009953dorsal/ventral pattern formationIEA
GO:0010259multicellular organismal agingIEA
GO:0010460positive regulation of heart rateIDA
GO:0010595positive regulation of endothelial cell migrationTAS
GO:0010613positive regulation of cardiac muscle hypertrophyIDA
GO:0010870positive regulation of receptor biosynthetic processIDA
GO:0014032neural crest cell developmentIEA
GO:0014065phosphatidylinositol 3-kinase cascadeIDA
GO:0014824artery smooth muscle contractionIDA
GO:0014824artery smooth muscle contractionTAS
GO:0014826vein smooth muscle contractionIDA
GO:0015758glucose transportIEA
GO:0016049cell growthIEA
GO:0019229regulation of vasoconstrictionIEA
GO:0019722calcium-mediated signalingIDA
GO:0030072peptide hormone secretionIDA
GO:0030185nitric oxide transportIDA
GO:0030195negative regulation of blood coagulationTAS
GO:0030335positive regulation of cell migrationIDA
GO:0030593neutrophil chemotaxisIDA
GO:0030818negative regulation of cAMP biosynthetic processIEA
GO:0031583activation of phospholipase D activity by G-protein coupled receptor protein signaling pathwayIEA
GO:0032269negative regulation of cellular protein metabolic processIDA
GO:0032496response to lipopolysaccharideIEA
GO:0033574response to testosterone stimulusIEA
GO:0034392negative regulation of smooth muscle cell apoptosisIEA
GO:0035094response to nicotineIEA
GO:0035810positive regulation of urine volumeIEA
GO:0035815positive regulation of renal sodium excretionIEA
GO:0042045epithelial fluid transportIEA
GO:0042310vasoconstrictionIDA
GO:0042313protein kinase C deactivationIDA
GO:0042474middle ear morphogenesisIEA
GO:0042482positive regulation of odontogenesisIEA
GO:0042493response to drugIEA
GO:0042554superoxide anion generationIEA
GO:0043179rhythmic excitationIEA
GO:0043200response to amino acid stimulusIEA
GO:0043406positive regulation of MAP kinase activityIDA
GO:0043507positive regulation of JUN kinase activityIDA
GO:0045321leukocyte activationTAS
GO:0045429positive regulation of nitric oxide biosynthetic processTAS
GO:0045793positive regulation of cell sizeIDA
GO:0045840positive regulation of mitosisIDA
GO:0045987positive regulation of smooth muscle contractionIEA
GO:0046887positive regulation of hormone secretionIDA
GO:0046888negative regulation of hormone secretionIEA
GO:0048016inositol phosphate-mediated signalingIDA
GO:0048514blood vessel morphogenesisIEA
GO:0048661positive regulation of smooth muscle cell proliferationIDA
GO:0051216cartilage developmentIEA
GO:0051482elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messengerIEA
GO:0051771negative regulation of nitric-oxide synthase biosynthetic processIDA
GO:0051899membrane depolarizationIEA
GO:0051930regulation of sensory perception of painIEA
GO:0060137maternal process involved in parturitionIEA
GO:0060298positive regulation of sarcomere organizationIMP
GO:0060585positive regulation of prostaglandin-endoperoxide synthase activityIMP
GO:0070101positive regulation of chemokine-mediated signaling pathwayIC
GO:0071347cellular response to interleukin-1IEA
GO:0071356cellular response to tumor necrosis factorIEA
GO:0090023positive regulation of neutrophil chemotaxisIEA
cellular_component
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIDA
GO:0005737cytoplasmIDA
molecular_function
GO:0005125cytokine activityIDA
GO:0005179hormone activityIDA
GO:0031707endothelin A receptor bindingIDA
GO:0031708endothelin B receptor bindingIDA
GO:0031708endothelin B receptor bindingIPI

Protein-protein interaction details for EDN1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
BAT3Two-hybridphysical16169070
COPS6Two-hybridphysical16169070