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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Ptpn11 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000077DNA damage checkpointIMP
GO:0000187activation of MAPK activityIMP
GO:0006470protein dephosphorylationISO
GO:0006629lipid metabolic processIMP
GO:0006641triglyceride metabolic processIMP
GO:0007409axonogenesisIMP
GO:0009755hormone-mediated signaling pathwayIDA
GO:0009967positive regulation of signal transductionIMP
GO:0016311dephosphorylationIMP
GO:0033628regulation of cell adhesion mediated by integrinISO
GO:0035265organ growthIMP
GO:0035335peptidyl-tyrosine dephosphorylationISO
GO:0040014regulation of multicellular organism growthIMP
GO:0042445hormone metabolic processIMP
GO:0042593glucose homeostasisIMP
GO:0046676negative regulation of insulin secretionIMP
GO:0046825regulation of protein export from nucleusIMP
GO:0046887positive regulation of hormone secretionIMP
GO:0046888negative regulation of hormone secretionIMP
GO:0048011nerve growth factor receptor signaling pathwayIMP
GO:0048013ephrin receptor signaling pathwayISO
GO:0048609multicellular organismal reproductive processIMP
GO:0051463negative regulation of cortisol secretionIMP
GO:0060125negative regulation of growth hormone secretionIMP
cellular_component
GO:0001725stress fiberISS
GO:0005624membrane fractionISS
GO:0005625soluble fractionISO
GO:0005737cytoplasmISO
GO:0005739mitochondrionISO
GO:0005829cytosolISO
GO:0030054cell junctionISS
GO:0043234protein complexISO
molecular_function
GO:0004721phosphoprotein phosphatase activityIMP
GO:0004725protein tyrosine phosphatase activityISO
GO:0004726non-membrane spanning protein tyrosine phosphatase activityISO
GO:0005158insulin receptor bindingISO
GO:0005515protein bindingIPI
GO:0016787hydrolase activityIEA
GO:0016791phosphatase activityIEA
GO:0019904protein domain specific bindingISO
GO:0043274phospholipase bindingISO
GO:0043560insulin receptor substrate bindingISO
GO:0051428peptide hormone receptor bindingIPI

Protein-protein interaction details for Ptpn11 (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
TekReconstituted Complexphysical10521483
ItchAffinity Capture-Westernphysical20417562