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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Rb1 (Mus musculus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000082 G1/S transition of mitotic cell cycle IMP GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0000122 negative regulation of transcription from RNA polymerase II promoter IGI GO:0006351 transcription, DNA-dependent IEA GO:0006355 regulation of transcription, DNA-dependent IEA GO:0006469 negative regulation of protein kinase activity ISO GO:0007049 cell cycle IEA GO:0007050 cell cycle arrest IMP GO:0007090 regulation of S phase of mitotic cell cycle IMP GO:0007346 regulation of mitotic cell cycle IMP GO:0007346 regulation of mitotic cell cycle ISO GO:0008285 negative regulation of cell proliferation IGI GO:0008285 negative regulation of cell proliferation IMP GO:0016568 chromatin modification IEA GO:0030182 neuron differentiation IMP GO:0031134 sister chromatid biorientation ISO GO:0031175 neuron projection development IMP GO:0034088 maintenance of mitotic sister chromatid cohesion ISO GO:0042551 neuron maturation IMP GO:0043353 enucleate erythrocyte differentiation IGI GO:0043550 regulation of lipid kinase activity ISO GO:0045445 myoblast differentiation ISO GO:0045651 positive regulation of macrophage differentiation IGI GO:0045786 negative regulation of cell cycle IMP GO:0045842 positive regulation of mitotic metaphase/anaphase transition ISO GO:0045879 negative regulation of smoothened signaling pathway IMP GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045892 negative regulation of transcription, DNA-dependent ISO GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IGI GO:0045944 positive regulation of transcription from RNA polymerase II promoter IMP GO:0048565 digestive tract development IMP GO:0048667 cell morphogenesis involved in neuron differentiation IMP GO:0050680 negative regulation of epithelial cell proliferation IMP GO:0051146 striated muscle cell differentiation IGI GO:0051301 cell division IMP GO:0051402 neuron apoptosis IMP GO:0051726 regulation of cell cycle IMP GO:0071459 protein localization to chromosome, centromeric region ISO GO:0071922 regulation of cohesin localization to chromatin ISO cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus ISO GO:0005667 transcription factor complex IDA GO:0005819 spindle IDA GO:0016605 PML body ISO molecular_function GO:0003677 DNA binding IEA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0008134 transcription factor binding ISO GO:0019899 enzyme binding IPI GO:0019900 kinase binding ISO GO:0031625 ubiquitin protein ligase binding ISO GO:0051219 phosphoprotein binding ISO

Protein-protein interaction details for Rb1 (Mus musculus) (Information is obtained from BioGRID)

Interacting mouse protein Experiment Type PubMed ID Hdac1 Affinity Capture-Western physical 11684023 Hdac1 Affinity Capture-Western physical 11684023 Smarca4 Two-hybrid physical 7923370 E2f2 Affinity Capture-Western physical 19513100 Hdac1 Reconstituted Complex physical 19633359 Hmga1 Reconstituted Complex physical 19633359 Hmga1 Affinity Capture-Western physical 19633359 Hmga1 Affinity Capture-Western physical 19633359 Runx2 Two-hybrid physical 20211142 Cebpd Two-hybrid physical 20211142 Id2 Two-hybrid physical 20211142 Hmga2 Affinity Capture-Western physical 16766265 Ubtf Co-fractionation physical 16582105 Hdac1 Affinity Capture-Western physical 10409740 Suv420h2 Reconstituted Complex physical 15750587 Suv420h1 Reconstituted Complex physical 15750587