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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for APLF (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000012single strand break repairIMP
GO:0006302double-strand break repairIMP
GO:0006974response to DNA damage stimulusIDA
cellular_component
GO:0005634nucleusIDA
GO:0005737cytoplasmIEA
GO:0005829cytosolIEA
molecular_function
GO:0000166nucleotide bindingIDA
GO:0003906DNA-(apurinic or apyrimidinic site) lyase activityIDA
GO:0004520endodeoxyribonuclease activityIDA
GO:0005515protein bindingIPI
GO:00084083'-5' exonuclease activityIDA
GO:0016829lyase activityIEA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for APLF (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
CHD1LAffinity Capture-Westernphysical19661379
PARP1Reconstituted Complexphysical17396150
PARP1Reconstituted Complexphysical17396150
LIG4Reconstituted Complexphysical17396150
XRCC5Reconstituted Complexphysical17396150
PARP1Reconstituted Complexphysical20098424