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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for EPAS1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001525 angiogenesis IEA GO:0001666 response to hypoxia IDA GO:0001666 response to hypoxia IEA GO:0001892 embryonic placenta development IEA GO:0001974 blood vessel remodeling IEA GO:0002027 regulation of heart rate IEA GO:0006366 transcription from RNA polymerase II promoter TAS GO:0006979 response to oxidative stress IEA GO:0007005 mitochondrion organization IEA GO:0007165 signal transduction TAS GO:0007275 multicellular organismal development IEA GO:0007601 visual perception IEA GO:0030097 hemopoiesis IEA GO:0030154 cell differentiation IEA GO:0030218 erythrocyte differentiation IEA GO:0030324 lung development IEA GO:0042415 norepinephrine metabolic process IEA GO:0043129 surfactant homeostasis IEA GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IGI GO:0048469 cell maturation IEA GO:0048625 myoblast cell fate commitment IEA GO:0048625 myoblast cell fate commitment ISS cellular_component GO:0005634 nucleus IEA GO:0005667 transcription factor complex IDA GO:0005667 transcription factor complex IEA GO:0005667 transcription factor complex IPI GO:0005737 cytoplasm IEA molecular_function GO:0003677 DNA binding IGI GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0004871 signal transducer activity IEA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IEA GO:0008134 transcription factor binding IPI GO:0035035 histone acetyltransferase binding IPI GO:0043565 sequence-specific DNA binding IDA GO:0043565 sequence-specific DNA binding IEA GO:0046982 protein heterodimerization activity IEA GO:0046982 protein heterodimerization activity IPI

Protein-protein interaction details for EPAS1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PSMC3 Affinity Capture-Western physical 14556007 ARNT Two-hybrid physical 9079689 ARNT Reconstituted Complex physical 9079689 ARNTL Two-hybrid physical 9576906 ARNTL Reconstituted Complex physical 9576906 VHL Affinity Capture-Western physical 17967880 EGLN1 Reconstituted Complex physical 16407130 APC Two-hybrid physical 20936779 MEF2C Two-hybrid physical 20936779 ARNT2 Two-hybrid physical 20211142 VHL Affinity Capture-Western physical 12604794 MAX Affinity Capture-Western physical 17418410 VHL Affinity Capture-Western physical 11331613 VHL Affinity Capture-Western physical 10878807 VHL Affinity Capture-Western physical 10823831 VHL Reconstituted Complex physical 10823831 MCM3 Affinity Capture-Western physical 21658608 MCM7 Affinity Capture-Western physical 21658608 F12 Affinity Capture-Western physical 21512133 F12 Affinity Capture-Western physical 21512133 F12 Reconstituted Complex physical 21512133 STUB1 Affinity Capture-Western physical 19940151 HSPA4 Affinity Capture-Western physical 19940151 SUMO1 Affinity Capture-Western physical 20026589 SUMO2 Affinity Capture-Western physical 20026589