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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for EPS15 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0007173 epidermal growth factor receptor signaling pathway TAS GO:0008283 cell proliferation TAS GO:0015031 protein transport IEA GO:0016050 vesicle organization TAS GO:0032456 endocytic recycling IC GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway TAS GO:0048268 clathrin coat assembly IDA cellular_component GO:0005737 cytoplasm IDA GO:0005768 endosome IEA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA GO:0005905 coated pit TAS GO:0030122 AP-2 adaptor complex IEA GO:0030136 clathrin-coated vesicle IEA GO:0031901 early endosome membrane IEA GO:0043231 intracellular membrane-bounded organelle IDA molecular_function GO:0004872 receptor activity IEA GO:0005509 calcium ion binding IEA GO:0005515 protein binding IPI GO:0017124 SH3 domain binding IEA

Protein-protein interaction details for EPS15 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID AGFG1 Two-hybrid physical 10613896 RNF11 Two-hybrid physical 14755250 SNAP91 Reconstituted Complex physical 12807910 AGFG1 Phenotypic Enhancement genetic 10613896 AGFG1 Affinity Capture-Western physical 10613896 AGFG1 Affinity Capture-Western physical 10613896 AGFG1 Co-fractionation physical 10613896 AGFG2 Co-fractionation physical 10613896 NAGPA Reconstituted Complex physical 11723124 STON2 Two-hybrid physical 11381094 STON2 Affinity Capture-Western physical 11381094 STON2 Reconstituted Complex physical 11381094 HGS Reconstituted Complex physical 10809762 HGS Two-hybrid physical 10809762 AP2A2 Reconstituted Complex physical 10809762 DNM2 Affinity Capture-Western physical 11483962 AP2A1 Affinity Capture-Western physical 9049247 EGFR Affinity Capture-Western physical 9049247 CLINT1 Reconstituted Complex physical 12429846 EPN1 Affinity Capture-Western physical 9723620 EPN1 Reconstituted Complex physical 9723620 SCAMP1 Two-hybrid physical 10777571 HGS Co-fractionation physical 12551915 STAM2 Affinity Capture-Western physical 12551915 GRB2 Far Western physical 7797522 CRK Far Western physical 7797522 CRK Reconstituted Complex physical 7797522 RAB11FIP2 Affinity Capture-Western physical 12364336 REPS2 Affinity Capture-Western physical 10393179 REPS2 Far Western physical 10393179 UBE2D1 Biochemical Activity physical 17588522 UBE2D2 Biochemical Activity physical 17588522 UBE2D3 Biochemical Activity physical 17588522 UBE2H Biochemical Activity physical 17588522 UBE2E1 Biochemical Activity physical 17588522 SLC6A3 Affinity Capture-Western physical 16885233 PARK2 Reconstituted Complex physical 16862145 PARK2 Biochemical Activity physical 16862145 UBC Affinity Capture-Western physical 16771824 USP8 Affinity Capture-Western physical 16771824 UBC Affinity Capture-Western physical 16735510 UBC Reconstituted Complex physical 16497223 CD4 Affinity Capture-Western physical 16497223 EGFR Affinity Capture-Western physical 15701692 EPS15 Affinity Capture-Western physical 12957285 UBC Affinity Capture-Western physical 12072436 UBC Affinity Capture-Western physical 9162018 OCLN Affinity Capture-Western physical 19478092 UBQLN1 Reconstituted Complex physical 17082820 UBQLN1 Reconstituted Complex physical 17082820 UBC Affinity Capture-Western physical 17013377 UBC Reconstituted Complex physical 17013377 NEDD4 Biochemical Activity physical 17013377 GJA1 Affinity Capture-Western physical 21554242 EGFR Affinity Capture-Western physical 21226813 UBC Reconstituted Complex physical 19880507 TGFB1 Affinity Capture-Western physical 19109251 TGFB1 Co-localization physical 19109251 UBC Affinity Capture-Western physical 19109251 EGFR Affinity Capture-Western physical 19109251 TGFB1 Affinity Capture-Western physical 19109251 GRB2 Affinity Capture-Western physical 19109251 GRB2 Affinity Capture-Western physical 19109251 GRB2 Reconstituted Complex physical 19109251 EGFR Affinity Capture-Western physical 19109251 GJA1 Affinity Capture-Western physical 19835873 PSMD4 Biochemical Activity physical 19240029 UBC Affinity Capture-MS physical 21987572 FCHO2 Affinity Capture-Western physical 21762413