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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ERCC1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000718 nucleotide-excision repair, DNA damage removal TAS GO:0000720 pyrimidine dimer repair by nucleotide-excision repair IEA GO:0001302 replicative cell aging IEA GO:0006281 DNA repair IEA GO:0006281 DNA repair TAS GO:0006283 transcription-coupled nucleotide-excision repair TAS GO:0006289 nucleotide-excision repair IDA GO:0006289 nucleotide-excision repair IGI GO:0006289 nucleotide-excision repair TAS GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion IMP GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion IMP GO:0006302 double-strand break repair IEA GO:0006310 DNA recombination IEA GO:0006310 DNA recombination IGI GO:0006312 mitotic recombination IMP GO:0006949 syncytium formation IEA GO:0006979 response to oxidative stress IMP GO:0007281 germ cell development IEA GO:0007283 spermatogenesis IEA GO:0007584 response to nutrient IEA GO:0008283 cell proliferation IEA GO:0008584 male gonad development IEA GO:0009628 response to abiotic stimulus IEA GO:0009650 UV protection IEA GO:0009744 response to sucrose stimulus IEA GO:0010165 response to X-ray IEA GO:0010259 multicellular organismal aging IEA GO:0032205 negative regulation of telomere maintenance IMP GO:0035166 post-embryonic hemopoiesis IEA GO:0035264 multicellular organism growth IEA GO:0043066 negative regulation of apoptosis IEA GO:0045190 isotype switching IEA GO:0048477 oogenesis IEA GO:0048568 embryonic organ development IEA GO:0051276 chromosome organization IEA cellular_component GO:0000109 nucleotide-excision repair complex IDA GO:0000784 nuclear chromosome, telomeric region IDA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA molecular_function GO:0000014 single-stranded DNA specific endodeoxyribonuclease activity IDA GO:0003684 damaged DNA binding IDA GO:0003684 damaged DNA binding IEA GO:0003697 single-stranded DNA binding IDA GO:0004519 endonuclease activity IEA GO:0005515 protein binding IPI GO:0008022 protein C-terminus binding IPI GO:0016787 hydrolase activity IEA GO:0019904 protein domain specific binding IPI GO:0043566 structure-specific DNA binding IDA

Protein-protein interaction details for ERCC1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID UBL7 Two-hybrid physical 16189514 XPA Two-hybrid physical 8197174 XPA Reconstituted Complex physical 8197174 XPA Two-hybrid physical 8197174 ERCC4 Reconstituted Complex physical 9722633 XPA Reconstituted Complex physical 7598728 XPA Two-hybrid physical 7598728 ERCC4 Reconstituted Complex physical 8197175 BTBD12 Affinity Capture-MS physical 19596235 GIYD2 Affinity Capture-MS physical 19596235 BTBD12 Two-hybrid physical 19596235 FANCG Two-hybrid physical 20518486 FANCG Affinity Capture-Western physical 20518486 FANCG Affinity Capture-Western physical 20518486 ERCC4 Reconstituted Complex physical 17289582 GTF2H1 Affinity Capture-Western physical 11259578