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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Sox2 (
Mus musculus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
IGI
GO:0001649
osteoblast differentiation
ISO
GO:0001708
cell fate specification
IMP
GO:0001714
endodermal cell fate specification
ISO
GO:0002052
positive regulation of neuroblast proliferation
IMP
GO:0006351
transcription, DNA-dependent
ISO
GO:0006355
regulation of transcription, DNA-dependent
IDA
GO:0006355
regulation of transcription, DNA-dependent
ISO
GO:0006357
regulation of transcription from RNA polymerase II promoter
IDA
GO:0007050
cell cycle arrest
ISO
GO:0007275
multicellular organismal development
IEA
GO:0007605
sensory perception of sound
IMP
GO:0010468
regulation of gene expression
ISO
GO:0019827
stem cell maintenance
IMP
GO:0021879
forebrain neuron differentiation
IMP
GO:0021984
adenohypophysis development
IMP
GO:0021987
cerebral cortex development
IMP
GO:0030178
negative regulation of Wnt receptor signaling pathway
IGI
GO:0030539
male genitalia development
IMP
GO:0030858
positive regulation of epithelial cell differentiation
IDA
GO:0030910
olfactory placode formation
IGI
GO:0032526
response to retinoic acid
IDA
GO:0035019
somatic stem cell maintenance
ISO
GO:0042221
response to chemical stimulus
IDA
GO:0042472
inner ear morphogenesis
IMP
GO:0043281
regulation of cysteine-type endopeptidase activity involved in apoptotic process
ISO
GO:0043410
positive regulation of MAPKKK cascade
ISO
GO:0043586
tongue development
IMP
GO:0045165
cell fate commitment
IDA
GO:0045596
negative regulation of cell differentiation
IMP
GO:0045665
negative regulation of neuron differentiation
IDA
GO:0045666
positive regulation of neuron differentiation
IMP
GO:0045668
negative regulation of osteoblast differentiation
IDA
GO:0045747
positive regulation of Notch signaling pathway
IDA
GO:0045893
positive regulation of transcription, DNA-dependent
ISO
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IDA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IGI
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IMP
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISO
GO:0046148
pigment biosynthetic process
IMP
GO:0048286
lung alveolus development
IDA
GO:0048568
embryonic organ development
IMP
GO:0048646
anatomical structure formation involved in morphogenesis
IMP
GO:0048663
neuron fate commitment
IMP
GO:0048852
diencephalon morphogenesis
IMP
GO:0048863
stem cell differentiation
IDA
GO:0050680
negative regulation of epithelial cell proliferation
ISO
GO:0050910
detection of mechanical stimulus involved in sensory perception of sound
IMP
GO:0050973
detection of mechanical stimulus involved in equilibrioception
IMP
GO:0060042
retina morphogenesis in camera-type eye
IMP
GO:0060235
lens induction in camera-type eye
IGI
GO:0060441
epithelial tube branching involved in lung morphogenesis
IDA
GO:0070848
response to growth factor stimulus
ISO
GO:0090090
negative regulation of canonical Wnt receptor signaling pathway
IDA
GO:0090090
negative regulation of canonical Wnt receptor signaling pathway
ISO
cellular_component
GO:0005625
soluble fraction
IDA
GO:0005634
nucleus
IC
GO:0005634
nucleus
IDA
GO:0005634
nucleus
ISO
GO:0005667
transcription factor complex
IDA
GO:0005737
cytoplasm
IDA
GO:0005737
cytoplasm
ISO
GO:0005829
cytosol
ISO
molecular_function
GO:0000976
transcription regulatory region sequence-specific DNA binding
ISO
GO:0001077
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
ISO
GO:0003677
DNA binding
IDA
GO:0003677
DNA binding
IGI
GO:0003677
DNA binding
ISO
GO:0003682
chromatin binding
IDA
GO:0003700
sequence-specific DNA binding transcription factor activity
IDA
GO:0003700
sequence-specific DNA binding transcription factor activity
ISO
GO:0005515
protein binding
IPI
GO:0008134
transcription factor binding
IPI
GO:0035198
miRNA binding
ISO
GO:0043565
sequence-specific DNA binding
IDA
GO:0043565
sequence-specific DNA binding
ISO
GO:0044212
transcription regulatory region DNA binding
IDA
GO:0044212
transcription regulatory region DNA binding
ISO
Protein-protein interaction details for Sox2 (
Mus musculus
)
(Information is obtained from BioGRID)
Interacting mouse protein
Experiment
Type
PubMed ID
Alx4
Two-hybrid
physical
20211142
Erg
Two-hybrid
physical
20211142
Pax6
Two-hybrid
physical
20211142
Pou5f1
Affinity Capture-MS
physical
20362541
Nanog
Affinity Capture-Western
physical
18454139
Xpo4
Affinity Capture-MS
physical
19349578
Xpo4
Affinity Capture-Western
physical
19349578
Xpo4
Reconstituted Complex
physical
19349578
Ctnnb1
Phenotypic Suppression
genetic
15781477
Ctnnb1
Affinity Capture-Western
physical
15781477
Ube2i
Biochemical Activity
physical
17097055
Uba2
Biochemical Activity
physical
17097055
Sae1
Biochemical Activity
physical
17097055
Pou5f1
Affinity Capture-Western
physical
15863505
Pou5f1
Affinity Capture-Western
physical
15863505
Hdac1
Reconstituted Complex
physical
21321941
Hdac1
Affinity Capture-Western
physical
21321941
Ubc
Affinity Capture-Western
physical
19591226