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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Sphk1 (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001568blood vessel developmentIGI
GO:0001934positive regulation of protein phosphorylationISO
GO:0001956positive regulation of neurotransmitter secretionISO
GO:0006670sphingosine metabolic processISO
GO:0006954inflammatory responseIMP
GO:0007205activation of protein kinase C activity by G-protein coupled receptor protein signaling pathwayIEA
GO:0007420brain developmentIGI
GO:0008284positive regulation of cell proliferationIGI
GO:0010803regulation of tumor necrosis factor-mediated signaling pathwayISO
GO:0010976positive regulation of neuron projection developmentISO
GO:0016310phosphorylationIEA
GO:0019371cyclooxygenase pathwayISO
GO:0019722calcium-mediated signalingISO
GO:0030307positive regulation of cell growthISO
GO:0030335positive regulation of cell migrationISO
GO:0031398positive regulation of protein ubiquitinationISO
GO:0032651regulation of interleukin-1 beta productionIMP
GO:0042346positive regulation of NF-kappaB import into nucleusISO
GO:0043066negative regulation of apoptosisISO
GO:0045766positive regulation of angiogenesisISO
GO:0045931positive regulation of mitotic cell cycleISO
GO:0045987positive regulation of smooth muscle contractionISO
GO:0046834lipid phosphorylationISA
GO:0046834lipid phosphorylationISO
GO:0048146positive regulation of fibroblast proliferationISO
GO:0051092positive regulation of NF-kappaB transcription factor activityISO
cellular_component
GO:0005624membrane fractionISO
GO:0005625soluble fractionISO
GO:0005634nucleusIEA
GO:0005737cytoplasmISO
GO:0005829cytosolISO
GO:0005886plasma membraneISO
GO:0008021synaptic vesicleISO
GO:0030424axonISO
GO:0043005neuron projectionISO
molecular_function
GO:0000166nucleotide bindingIEA
GO:0000287magnesium ion bindingISO
GO:0003677DNA bindingISA
GO:0004143diacylglycerol kinase activityIEA
GO:0005516calmodulin bindingISA
GO:0005516calmodulin bindingISO
GO:0005524ATP bindingISO
GO:0008481sphinganine kinase activityISA
GO:0008481sphinganine kinase activityISO
GO:0016301kinase activityIEA
GO:0016740transferase activityIEA
GO:0017050D-erythro-sphingosine kinase activityISO
GO:0051721protein phosphatase 2A bindingISO

Protein-protein interaction details for Sphk1 (Mus musculus)
(Information is obtained from BioGRID)
Not available