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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ALAS2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001666 response to hypoxia IDA GO:0006778 porphyrin-containing compound metabolic process IEA GO:0006778 porphyrin-containing compound metabolic process TAS GO:0006783 heme biosynthetic process ISS GO:0006783 heme biosynthetic process NAS GO:0006783 heme biosynthetic process TAS GO:0006879 cellular iron ion homeostasis ISS GO:0009058 biosynthetic process IEA GO:0030218 erythrocyte differentiation ISS GO:0030218 erythrocyte differentiation NAS GO:0032364 oxygen homeostasis NAS GO:0033014 tetrapyrrole biosynthetic process IEA GO:0042541 hemoglobin biosynthetic process ISS cellular_component GO:0005739 mitochondrion IDA GO:0005743 mitochondrial inner membrane IDA GO:0005759 mitochondrial matrix IEA GO:0005759 mitochondrial matrix TAS molecular_function GO:0003870 5-aminolevulinate synthase activity IDA GO:0003870 5-aminolevulinate synthase activity IEA GO:0005515 protein binding IPI GO:0016594 glycine binding ISS GO:0016746 transferase activity, transferring acyl groups IEA GO:0016769 transferase activity, transferring nitrogenous groups IEA GO:0030170 pyridoxal phosphate binding IEA GO:0050662 coenzyme binding ISS

Protein-protein interaction details for ALAS2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SUCLA2 Affinity Capture-Western physical 10727444 GRB2 Two-hybrid physical 18624398