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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MECOM (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001701 in utero embryonic development IEA GO:0001780 neutrophil homeostasis IEA GO:0006351 transcription, DNA-dependent IDA GO:0006351 transcription, DNA-dependent TAS GO:0006355 regulation of transcription, DNA-dependent TAS GO:0006915 apoptosis IEA GO:0006954 inflammatory response IEA GO:0009605 response to external stimulus IEA GO:0009617 response to bacterium IEA GO:0009791 post-embryonic development IEA GO:0030154 cell differentiation IEA GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IDA GO:0030900 forebrain development IEA GO:0035115 embryonic forelimb morphogenesis IEA GO:0035116 embryonic hindlimb morphogenesis IEA GO:0042127 regulation of cell proliferation IEA GO:0043069 negative regulation of programmed cell death IMP GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045892 negative regulation of transcription, DNA-dependent IEA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0046329 negative regulation of JNK cascade IMP GO:0051726 regulation of cell cycle IDA GO:0060039 pericardium development IEA GO:0071425 hemopoietic stem cell proliferation IEA GO:0071425 hemopoietic stem cell proliferation ISS cellular_component GO:0000118 histone deacetylase complex IDA GO:0005622 intracellular IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0016607 nuclear speck IDA molecular_function GO:0003676 nucleic acid binding IEA GO:0003677 DNA binding IEA GO:0003677 DNA binding ISS GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003700 sequence-specific DNA binding transcription factor activity TAS GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0042803 protein homodimerization activity IDA GO:0046872 metal ion binding IEA

Protein-protein interaction details for MECOM (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HDAC1 Affinity Capture-Western physical 11552981 HDAC1 Reconstituted Complex physical 11552981 CTBP1 Affinity Capture-Western physical 11568182 HDAC1 Affinity Capture-Western physical 11568182 HDAC4 Affinity Capture-Western physical 11568182 CREBBP Affinity Capture-Western physical 11568182 KAT2B Affinity Capture-Western physical 11568182 CTBP1 Phenotypic Enhancement genetic 11568182 CTBP1 Phenotypic Suppression genetic 11568182 CREBBP Biochemical Activity physical 11568182 KAT2B Biochemical Activity physical 11568182 SMAD3 Affinity Capture-Western physical 9665135 SMAD3 Reconstituted Complex physical 9665135 CTBP1 Affinity Capture-Western physical 11313276 CTBP1 Reconstituted Complex physical 11313276 MBD3 Affinity Capture-Western physical 18500823 MBD3 Affinity Capture-Western physical 18500823 MBD3 Two-hybrid physical 18500823 MBD3 Reconstituted Complex physical 18500823 SUV39H1 Affinity Capture-Western physical 18655152 SUV39H1 Reconstituted Complex physical 18655152 SUV39H1 Affinity Capture-Western physical 18619962 EHMT2 Affinity Capture-Western physical 18619962 SMAD3 Affinity Capture-Western physical 15849193 SMAD1 Reconstituted Complex physical 15849193 SMAD2 Reconstituted Complex physical 15849193 SMAD3 Reconstituted Complex physical 15849193 SMAD4 Reconstituted Complex physical 15849193 KAT2B Affinity Capture-Western physical 20363750 KAT2B Affinity Capture-Western physical 20363750