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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for Tcf7l2 (
Mus musculus
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
ISO
GO:0001568
blood vessel development
ISO
GO:0006351
transcription, DNA-dependent
ISO
GO:0006355
regulation of transcription, DNA-dependent
IDA
GO:0006357
regulation of transcription from RNA polymerase II promoter
IMP
GO:0006357
regulation of transcription from RNA polymerase II promoter
ISO
GO:0006916
anti-apoptosis
ISO
GO:0007050
cell cycle arrest
ISO
GO:0008283
cell proliferation
ISO
GO:0009749
response to glucose stimulus
IMP
GO:0010909
positive regulation of heparan sulfate proteoglycan biosynthetic process
ISO
GO:0014003
oligodendrocyte development
IMP
GO:0016055
Wnt receptor signaling pathway
IDA
GO:0016055
Wnt receptor signaling pathway
IGI
GO:0021915
neural tube development
IGI
GO:0021983
pituitary gland development
IMP
GO:0030282
bone mineralization
IGI
GO:0030514
negative regulation of BMP signaling pathway
IMP
GO:0030538
embryonic genitalia morphogenesis
IGI
GO:0031641
regulation of myelination
IMP
GO:0032024
positive regulation of insulin secretion
IMP
GO:0032024
positive regulation of insulin secretion
ISO
GO:0032092
positive regulation of protein binding
ISO
GO:0032252
secretory granule localization
IMP
GO:0032350
regulation of hormone metabolic process
ISO
GO:0035019
somatic stem cell maintenance
IGI
GO:0035019
somatic stem cell maintenance
IMP
GO:0035411
catenin import into nucleus
IDA
GO:0040037
negative regulation of fibroblast growth factor receptor signaling pathway
IMP
GO:0042475
odontogenesis of dentine-containing tooth
IGI
GO:0042593
glucose homeostasis
ISO
GO:0043065
positive regulation of apoptosis
IMP
GO:0043433
negative regulation of sequence-specific DNA binding transcription factor activity
ISO
GO:0043570
maintenance of DNA repeat elements
ISO
GO:0043588
skin development
IGI
GO:0044334
canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition
ISO
GO:0045444
fat cell differentiation
ISO
GO:0045599
negative regulation of fat cell differentiation
IMP
GO:0045892
negative regulation of transcription, DNA-dependent
ISO
GO:0045893
positive regulation of transcription, DNA-dependent
IMP
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IGI
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
ISO
GO:0046621
negative regulation of organ growth
IMP
GO:0046827
positive regulation of protein export from nucleus
ISO
GO:0048557
embryonic digestive tract morphogenesis
IGI
GO:0048619
embryonic hindgut morphogenesis
IGI
GO:0048625
myoblast cell fate commitment
IMP
GO:0048625
myoblast cell fate commitment
ISO
GO:0048641
regulation of skeletal muscle tissue development
IMP
GO:0048660
regulation of smooth muscle cell proliferation
ISO
GO:0048713
regulation of oligodendrocyte differentiation
IMP
GO:0050679
positive regulation of epithelial cell proliferation
IMP
GO:0051897
positive regulation of protein kinase B signaling cascade
ISO
GO:0060070
canonical Wnt receptor signaling pathway
IMP
GO:0060325
face morphogenesis
IGI
GO:0061178
regulation of insulin secretion involved in cellular response to glucose stimulus
IMP
GO:0061178
regulation of insulin secretion involved in cellular response to glucose stimulus
ISO
GO:0090090
negative regulation of canonical Wnt receptor signaling pathway
ISO
cellular_component
GO:0005634
nucleus
IDA
GO:0005634
nucleus
ISO
GO:0005654
nucleoplasm
ISO
GO:0005667
transcription factor complex
IDA
GO:0005829
cytosol
IDA
GO:0032993
protein-DNA complex
ISO
GO:0070369
beta-catenin-TCF7L2 complex
ISO
molecular_function
GO:0003677
DNA binding
IEA
GO:0003682
chromatin binding
IDA
GO:0003700
sequence-specific DNA binding transcription factor activity
IBA
GO:0003700
sequence-specific DNA binding transcription factor activity
ISO
GO:0005515
protein binding
IPI
GO:0008013
beta-catenin binding
IDA
GO:0008013
beta-catenin binding
IPI
GO:0008013
beta-catenin binding
ISO
GO:0008134
transcription factor binding
ISO
GO:0019901
protein kinase binding
ISO
GO:0035257
nuclear hormone receptor binding
ISO
GO:0043565
sequence-specific DNA binding
IBA
GO:0043565
sequence-specific DNA binding
ISO
GO:0044212
transcription regulatory region DNA binding
IBA
GO:0044212
transcription regulatory region DNA binding
ISO
GO:0045295
gamma-catenin binding
ISO
GO:0070016
armadillo repeat domain binding
ISO
Protein-protein interaction details for Tcf7l2 (
Mus musculus
)
(Information is obtained from BioGRID)
Interacting mouse protein
Experiment
Type
PubMed ID
Hnf4a
Affinity Capture-Western
physical
19805521
Hnf4a
Affinity Capture-Western
physical
19805521
Ctnnb1
Affinity Capture-Western
physical
19805521
Ctnnb1
Affinity Capture-Western
physical
19503085
Hdac1
Affinity Capture-Western
physical
19503085
Hdac2
Affinity Capture-Western
physical
19503085
Ctnnb1
Phenotypic Suppression
genetic
15778706
Ctnnb1
Affinity Capture-Western
physical
12861022
Ctnnb1
Phenotypic Suppression
genetic
12861022
Ctnnb1
Affinity Capture-Western
physical
17053159