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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FASN (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006112 energy reserve metabolic process TAS GO:0006631 fatty acid metabolic process TAS GO:0006633 fatty acid biosynthetic process IEA GO:0006766 vitamin metabolic process TAS GO:0006767 water-soluble vitamin metabolic process TAS GO:0009058 biosynthetic process IEA GO:0015939 pantothenate metabolic process TAS GO:0019432 triglyceride biosynthetic process TAS GO:0031325 positive regulation of cellular metabolic process TAS GO:0035338 long-chain fatty-acyl-CoA biosynthetic process TAS GO:0044255 cellular lipid metabolic process TAS cellular_component GO:0005737 cytoplasm IDA GO:0005739 mitochondrion IEA GO:0005794 Golgi apparatus IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA GO:0042470 melanosome IEA GO:0042587 glycogen granule IEA molecular_function GO:0000036 acyl carrier activity IEA GO:0004312 fatty acid synthase activity TAS GO:0004313 [acyl-carrier-protein] S-acetyltransferase activity IEA GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity IEA GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity IEA GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity IEA GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity IEA GO:0004319 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity IEA GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity IEA GO:0005488 binding IEA GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0016295 myristoyl-[acyl-carrier-protein] hydrolase activity IEA GO:0016296 palmitoyl-[acyl-carrier-protein] hydrolase activity IEA GO:0016491 oxidoreductase activity IEA GO:0016740 transferase activity IEA GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups IEA GO:0016788 hydrolase activity, acting on ester bonds IEA GO:0016829 lyase activity IEA GO:0031177 phosphopantetheine binding IEA GO:0048037 cofactor binding IEA

Protein-protein interaction details for FASN (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID FASN Two-hybrid physical 11248039 EWSR1 Two-hybrid physical 16189514 USP2 Reconstituted Complex physical 15050917 USP2 Affinity Capture-MS physical 15050917 UBC Affinity Capture-Western physical 15050917 USP2 Biochemical Activity physical 15050917 UBC Affinity Capture-MS physical 16335966 UBC Affinity Capture-MS physical 16196087 YWHAQ Affinity Capture-MS physical 15161933 HDAC5 Affinity Capture-MS physical 21081666 UBC Affinity Capture-MS physical 15852347 UBC Affinity Capture-MS physical 22178446 UBC Affinity Capture-MS physical 18781797 PCK1 Affinity Capture-MS physical 21726808 UBC Affinity Capture-MS physical 21987572