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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FECH (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006091generation of precursor metabolites and energyTAS
GO:0006778porphyrin-containing compound metabolic processTAS
GO:0006783heme biosynthetic processTAS
GO:0009416response to light stimulusTAS
GO:0046501protoporphyrinogen IX metabolic processIDA
cellular_component
GO:0005739mitochondrionIEA
GO:0005743mitochondrial inner membraneIEA
GO:0005759mitochondrial matrixTAS
GO:0016020membraneIEA
molecular_function
GO:0004325ferrochelatase activityIDA
GO:0004325ferrochelatase activityTAS
GO:0005515protein bindingIPI
GO:0008198ferrous iron bindingTAS
GO:0046872metal ion bindingIEA
GO:00515372 iron, 2 sulfur cluster bindingIEA

Protein-protein interaction details for FECH (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
ABCB7Reconstituted Complexphysical12480705
ABCB7Affinity Capture-Westernphysical12480705
FECHCo-crystal Structurephysical11175906
USP20Affinity Capture-MSphysical19615732
USP42Affinity Capture-MSphysical19615732
MMEAffinity Capture-MSphysical17342744
C1orf151Affinity Capture-MSphysical22114354