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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Wnt5a (Mus musculus)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterIBA
GO:0000187activation of MAPK activityISO
GO:0001667ameboidal cell migrationIMP
GO:0001736establishment of planar polarityIMP
GO:0001756somitogenesisIGI
GO:0001843neural tube closureIGI
GO:0001934positive regulation of protein phosphorylationIDA
GO:0001938positive regulation of endothelial cell proliferationISO
GO:0001947heart loopingIGI
GO:0002009morphogenesis of an epitheliumIMP
GO:0002053positive regulation of mesenchymal cell proliferationIMP
GO:0002741positive regulation of cytokine secretion involved in immune responseISO
GO:0003323type B pancreatic cell developmentIMP
GO:0003344pericardium morphogenesisIGI
GO:0003401axis elongationIMP
GO:0006351transcription, DNA-dependentISO
GO:0006468protein phosphorylationIGI
GO:0007165signal transductionTAS
GO:0007223Wnt receptor signaling pathway, calcium modulating pathwayIDA
GO:0007223Wnt receptor signaling pathway, calcium modulating pathwayIMP
GO:0007223Wnt receptor signaling pathway, calcium modulating pathwayISO
GO:0007254JNK cascadeIDA
GO:0007257activation of JUN kinase activityISO
GO:0007267cell-cell signalingTAS
GO:0007275multicellular organismal developmentIEA
GO:0007411axon guidanceIDA
GO:0007442hindgut morphogenesisIMP
GO:0007494midgut developmentIMP
GO:0008284positive regulation of cell proliferationIDA
GO:0008284positive regulation of cell proliferationIMP
GO:0008584male gonad developmentIMP
GO:0008595anterior/posterior axis specification, embryoIDA
GO:0009790embryo developmentIMP
GO:0009887organ morphogenesisTAS
GO:0009950dorsal/ventral axis specificationIBA
GO:0009952anterior/posterior pattern specificationIMP
GO:0010595positive regulation of endothelial cell migrationISO
GO:0010800positive regulation of peptidyl-threonine phosphorylationIGI
GO:0010820positive regulation of T cell chemotaxisISO
GO:0016055Wnt receptor signaling pathwayIGI
GO:0016055Wnt receptor signaling pathwayISO
GO:0016477cell migrationIGI
GO:0016477cell migrationIMP
GO:0021915neural tube developmentIGI
GO:0022409positive regulation of cell-cell adhesionISO
GO:0030154cell differentiationIEA
GO:0030324lung developmentIMP
GO:0030326embryonic limb morphogenesisIMP
GO:0030514negative regulation of BMP signaling pathwayIMP
GO:0030825positive regulation of cGMP metabolic processISO
GO:0032148activation of protein kinase B activityISO
GO:0032729positive regulation of interferon-gamma productionIMP
GO:0032755positive regulation of interleukin-6 productionIDA
GO:0032755positive regulation of interleukin-6 productionISO
GO:0033138positive regulation of peptidyl-serine phosphorylationIGI
GO:0034613cellular protein localizationIMP
GO:0034613cellular protein localizationISO
GO:0035108limb morphogenesisIMP
GO:0035121tail morphogenesisIGI
GO:0035121tail morphogenesisIMP
GO:0040037negative regulation of fibroblast growth factor receptor signaling pathwayIMP
GO:0042060wound healingISO
GO:0042472inner ear morphogenesisIDA
GO:0042472inner ear morphogenesisIMP
GO:0042733embryonic digit morphogenesisIMP
GO:0043032positive regulation of macrophage activationISO
GO:0043066negative regulation of apoptosisISO
GO:0043507positive regulation of JUN kinase activityIDA
GO:0043507positive regulation of JUN kinase activityIMP
GO:0045080positive regulation of chemokine biosynthetic processISO
GO:0045599negative regulation of fat cell differentiationISO
GO:0045732positive regulation of protein catabolic processISO
GO:0045766positive regulation of angiogenesisISO
GO:0045778positive regulation of ossificationISO
GO:0045836positive regulation of meiosisIGI
GO:0045892negative regulation of transcription, DNA-dependentISO
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentISO
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0046330positive regulation of JNK cascadeIMP
GO:0046546development of primary male sexual characteristicsIMP
GO:0048146positive regulation of fibroblast proliferationISO
GO:0048546digestive tract morphogenesisIMP
GO:0048706embryonic skeletal system developmentISO
GO:0048806genitalia developmentISO
GO:0048812neuron projection morphogenesisIDA
GO:0048843negative regulation of axon extension involved in axon guidanceIGI
GO:0048850hypophysis morphogenesisIMP
GO:0050679positive regulation of epithelial cell proliferationIMP
GO:0050680negative regulation of epithelial cell proliferationIDA
GO:0050680negative regulation of epithelial cell proliferationIMP
GO:0050718positive regulation of interleukin-1 beta secretionIDA
GO:0050718positive regulation of interleukin-1 beta secretionISO
GO:0050729positive regulation of inflammatory responseISO
GO:0050919negative chemotaxisIGI
GO:0051092positive regulation of NF-kappaB transcription factor activityISO
GO:0051216cartilage developmentIEA
GO:0051964negative regulation of synapse assemblyIDA
GO:0060021palate developmentISO
GO:0060026convergent extensionIMP
GO:0060029convergent extension involved in organogenesisIGI
GO:0060065uterus developmentIMP
GO:0060067cervix developmentIMP
GO:0060068vagina developmentIMP
GO:0060070canonical Wnt receptor signaling pathwayIDA
GO:0060070canonical Wnt receptor signaling pathwayIGI
GO:0060070canonical Wnt receptor signaling pathwayIMP
GO:0060071Wnt receptor signaling pathway, planar cell polarity pathwayIDA
GO:0060071Wnt receptor signaling pathway, planar cell polarity pathwayIGI
GO:0060071Wnt receptor signaling pathway, planar cell polarity pathwayIMP
GO:0060071Wnt receptor signaling pathway, planar cell polarity pathwayISO
GO:0060157urinary bladder developmentIMP
GO:0060324face developmentISO
GO:0060340positive regulation of type I interferon-mediated signaling pathwayISO
GO:0060599lateral sprouting involved in mammary gland duct morphogenesisIDA
GO:0060606tube closureIMP
GO:0060638mesenchymal-epithelial cell signalingIMP
GO:0060686negative regulation of prostatic bud formationIMP
GO:0060744mammary gland branching involved in thelarcheIDA
GO:0060750epithelial cell proliferation involved in mammary gland duct elongationIDA
GO:0060760positive regulation of response to cytokine stimulusISO
GO:0060762regulation of branching involved in mammary gland duct morphogenesisIDA
GO:0060762regulation of branching involved in mammary gland duct morphogenesisIGI
GO:0060907positive regulation of macrophage cytokine productionISO
GO:0061036positive regulation of cartilage developmentIDA
GO:0061036positive regulation of cartilage developmentIMP
GO:0061347planar cell polarity pathway involved in outflow tract morphogenesisIMP
GO:0061348planar cell polarity pathway involved in ventricular septum morphogenesisIMP
GO:0061349planar cell polarity pathway involved in cardiac right atrium morphogenesisIMP
GO:0061350planar cell polarity pathway involved in cardiac muscle tissue morphogenesisIMP
GO:0061354planar cell polarity pathway involved in pericardium morphogenesisIMP
GO:0070245positive regulation of thymocyte apoptosisIMP
GO:0071219cellular response to molecule of bacterial originIDA
GO:0071425hemopoietic stem cell proliferationIDA
GO:0071425hemopoietic stem cell proliferationIMP
GO:0071425hemopoietic stem cell proliferationISO
GO:0071542dopaminergic neuron differentiationIGI
GO:0071542dopaminergic neuron differentiationIMP
GO:0072201negative regulation of mesenchymal cell proliferationISO
GO:0090009primitive streak formationIGI
GO:0090037positive regulation of protein kinase C signaling cascadeISO
GO:0090090negative regulation of canonical Wnt receptor signaling pathwayIDA
GO:0090090negative regulation of canonical Wnt receptor signaling pathwayIGI
GO:0090090negative regulation of canonical Wnt receptor signaling pathwayIMP
GO:0090090negative regulation of canonical Wnt receptor signaling pathwayISO
GO:0090103cochlea morphogenesisIGI
GO:0090103cochlea morphogenesisIMP
GO:0090179planar cell polarity pathway involved in neural tube closureIMP
GO:2000049positive regulation of cell-cell adhesion mediated by cadherinIDA
GO:2000484positive regulation of interleukin-8 secretionIDA
cellular_component
GO:0005576extracellular regionIEA
GO:0005578proteinaceous extracellular matrixIEA
GO:0005615extracellular spaceIBA
GO:0005615extracellular spaceISO
GO:0005624membrane fractionISO
GO:0005737cytoplasmISO
GO:0005886plasma membraneIBA
GO:0009986cell surfaceIDA
GO:0031012extracellular matrixIDA
molecular_function
GO:0003700sequence-specific DNA binding transcription factor activityISO
GO:0005102receptor bindingIPI
GO:0005102receptor bindingTAS
GO:0005109frizzled bindingIPI
GO:0005109frizzled bindingISO
GO:0005110frizzled-2 bindingIDA
GO:0005115receptor tyrosine kinase-like orphan receptor bindingISO
GO:0005125cytokine activityIDA
GO:0005515protein bindingIPI
GO:0019904protein domain specific bindingIPI
GO:0044212transcription regulatory region DNA bindingISO

Protein-protein interaction details for Wnt5a (Mus musculus)
(Information is obtained from BioGRID)
Interacting mouse proteinExperimentTypePubMed ID
Lrp6Affinity Capture-Westernphysical19056682
Lrp6Affinity Capture-Westernphysical19056682
Lrp6Phenotypic Suppressiongenetic19056682
RykAffinity Capture-Westernphysical16723543
Ror2Reconstituted Complexphysical12839624
Ror2Phenotypic Enhancementgenetic12839624
PorcnAffinity Capture-Westernphysical10866835