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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FGFR2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS GO:0001525 angiogenesis ISS GO:0001657 ureteric bud development ISS GO:0001701 in utero embryonic development ISS GO:0002053 positive regulation of mesenchymal cell proliferation ISS GO:0003148 outflow tract septum morphogenesis ISS GO:0003149 membranous septum morphogenesis ISS GO:0007267 cell-cell signaling ISS GO:0007409 axonogenesis ISS GO:0008284 positive regulation of cell proliferation IDA GO:0008284 positive regulation of cell proliferation IEA GO:0008284 positive regulation of cell proliferation IGI GO:0008284 positive regulation of cell proliferation IMP GO:0008286 insulin receptor signaling pathway TAS GO:0008543 fibroblast growth factor receptor signaling pathway IDA GO:0008543 fibroblast growth factor receptor signaling pathway IGI GO:0008543 fibroblast growth factor receptor signaling pathway IPI GO:0008543 fibroblast growth factor receptor signaling pathway NAS GO:0008543 fibroblast growth factor receptor signaling pathway TAS GO:0008589 regulation of smoothened signaling pathway ISS GO:0009791 post-embryonic development ISS GO:0009880 embryonic pattern specification ISS GO:0009887 organ morphogenesis ISS GO:0010453 regulation of cell fate commitment ISS GO:0010518 positive regulation of phospholipase activity IMP GO:0016331 morphogenesis of embryonic epithelium ISS GO:0018108 peptidyl-tyrosine phosphorylation IDA GO:0021769 orbitofrontal cortex development ISS GO:0021847 ventricular zone neuroblast division ISS GO:0021860 pyramidal neuron development ISS GO:0022612 gland morphogenesis ISS GO:0030177 positive regulation of Wnt receptor signaling pathway ISS GO:0030282 bone mineralization ISS GO:0030324 lung development ISS GO:0030855 epithelial cell differentiation ISS GO:0030901 midbrain development ISS GO:0030916 otic vesicle formation ISS GO:0031069 hair follicle morphogenesis ISS GO:0032808 lacrimal gland development ISS GO:0033688 regulation of osteoblast proliferation TAS GO:0035264 multicellular organism growth ISS GO:0035265 organ growth ISS GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptosis in bone marrow ISS GO:0035603 fibroblast growth factor receptor signaling pathway involved in hemopoiesis ISS GO:0035604 fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow ISS GO:0035607 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development ISS GO:0040014 regulation of multicellular organism growth ISS GO:0040036 regulation of fibroblast growth factor receptor signaling pathway ISS GO:0042472 inner ear morphogenesis ISS GO:0042476 odontogenesis ISS GO:0043410 positive regulation of MAPKKK cascade IMP GO:0045165 cell fate commitment ISS GO:0045667 regulation of osteoblast differentiation TAS GO:0045787 positive regulation of cell cycle ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter ISS GO:0046777 protein autophosphorylation IDA GO:0048286 lung alveolus development ISS GO:0048557 embryonic digestive tract morphogenesis ISS GO:0048562 embryonic organ morphogenesis ISS GO:0048565 digestive tract development ISS GO:0048568 embryonic organ development ISS GO:0048608 reproductive structure development ISS GO:0048705 skeletal system morphogenesis TAS GO:0048730 epidermis morphogenesis ISS GO:0048755 branching morphogenesis of a nerve ISS GO:0048762 mesenchymal cell differentiation ISS GO:0050679 positive regulation of epithelial cell proliferation ISS GO:0051150 regulation of smooth muscle cell differentiation ISS GO:0051781 positive regulation of cell division ISS GO:0055010 ventricular cardiac muscle tissue morphogenesis ISS GO:0060045 positive regulation of cardiac muscle cell proliferation ISS GO:0060174 limb bud formation ISS GO:0060348 bone development ISS GO:0060349 bone morphogenesis ISS GO:0060442 branching involved in prostate gland morphogenesis ISS GO:0060445 branching involved in salivary gland morphogenesis ISS GO:0060449 bud elongation involved in lung branching ISS GO:0060463 lung lobe morphogenesis ISS GO:0060484 lung-associated mesenchyme development ISS GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis ISS GO:0060512 prostate gland morphogenesis ISS GO:0060523 prostate epithelial cord elongation ISS GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ISS GO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development ISS GO:0060595 fibroblast growth factor receptor signaling pathway involved in mammary gland specification ISS GO:0060601 lateral sprouting from an epithelium ISS GO:0060615 mammary gland bud formation ISS GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis ISS GO:0060667 branch elongation involved in salivary gland morphogenesis ISS GO:0060670 branching involved in embryonic placenta morphogenesis ISS GO:0060687 regulation of branching involved in prostate gland morphogenesis ISS GO:0060688 regulation of morphogenesis of a branching structure ISS GO:0060915 mesenchymal cell differentiation involved in lung development ISS GO:0060916 mesenchymal cell proliferation involved in lung development ISS GO:0070372 regulation of ERK1 and ERK2 cascade ISS GO:0070374 positive regulation of ERK1 and ERK2 cascade ISS GO:0090263 positive regulation of canonical Wnt receptor signaling pathway ISS cellular_component GO:0005576 extracellular region IEA GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane IDA GO:0005938 cell cortex IDA GO:0009986 cell surface IDA GO:0016020 membrane IEA GO:0016020 membrane NAS GO:0016021 integral to membrane IEA GO:0016021 integral to membrane NAS GO:0031012 extracellular matrix IDA GO:0060076 excitatory synapse ISS molecular_function GO:0000166 nucleotide binding IEA GO:0004713 protein tyrosine kinase activity IEA GO:0004713 protein tyrosine kinase activity NAS GO:0004872 receptor activity IEA GO:0005007 fibroblast growth factor-activated receptor activity IDA GO:0005007 fibroblast growth factor-activated receptor activity IEA GO:0005007 fibroblast growth factor-activated receptor activity IPI GO:0005007 fibroblast growth factor-activated receptor activity NAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0008201 heparin binding IEA GO:0017134 fibroblast growth factor binding IDA GO:0017134 fibroblast growth factor binding IPI GO:0042803 protein homodimerization activity IPI

Protein-protein interaction details for FGFR2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID FGF1 Co-crystal Structure physical 10618369 FGF1 Co-crystal Structure physical 11069186 FGFR2 Co-crystal Structure physical 11069186 FGF1 Reconstituted Complex physical 8576175 FGF7 Reconstituted Complex physical 9582367 FGF10 Reconstituted Complex physical 9582367 PIK3R1 Affinity Capture-Western physical 18374639 ITGA5 Affinity Capture-Western physical 15728256 ITGA5 Affinity Capture-Western physical 15728256 STAT3 Affinity Capture-Western physical 20388777 STAT3 Affinity Capture-Western physical 20388777 PGR Affinity Capture-Western physical 21464042 STAT5A Affinity Capture-Western physical 21464042 STAT5B Affinity Capture-Western physical 21464042 PGR Affinity Capture-Western physical 21464042 STAT5A Affinity Capture-Western physical 21464042 STAT5B Affinity Capture-Western physical 21464042 UBC Affinity Capture-Western physical 21596750 FRS2 Affinity Capture-Western physical 21596750