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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FKBP1A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000413 protein peptidyl-prolyl isomerization IDA GO:0000413 protein peptidyl-prolyl isomerization TAS GO:0003007 heart morphogenesis ISS GO:0006457 protein folding IEA GO:0006457 protein folding NAS GO:0006458 'de novo' protein folding TAS GO:0007165 signal transduction IMP GO:0007183 SMAD protein complex assembly IDA GO:0018208 peptidyl-proline modification IBA GO:0022417 protein maturation by protein folding TAS GO:0031398 positive regulation of protein ubiquitination IDA GO:0032092 positive regulation of protein binding IDA GO:0032513 negative regulation of protein phosphatase type 2B activity IDA GO:0032925 regulation of activin receptor signaling pathway IDA GO:0034205 beta-amyloid formation IDA GO:0042026 protein refolding TAS GO:0042110 T cell activation NAS GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IMP GO:0043206 fibril organization IDA GO:0050776 regulation of immune response IMP GO:0055010 ventricular cardiac muscle tissue morphogenesis ISS GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity IDA GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity ISS GO:0060347 heart trabecula formation ISS cellular_component GO:0005737 cytoplasm IEA GO:0005829 cytosol IDA GO:0014802 terminal cisterna ISS GO:0030424 axon IBA GO:0033017 sarcoplasmic reticulum membrane IBA molecular_function GO:0003755 peptidyl-prolyl cis-trans isomerase activity IDA GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA GO:0003755 peptidyl-prolyl cis-trans isomerase activity TAS GO:0004871 signal transducer activity IMP GO:0005024 transforming growth factor beta-activated receptor activity TAS GO:0005160 transforming growth factor beta receptor binding ISS GO:0005219 ryanodine-sensitive calcium-release channel activity TAS GO:0005515 protein binding IPI GO:0005527 macrolide binding NAS GO:0005528 FK506 binding IDA GO:0005528 FK506 binding NAS GO:0016853 isomerase activity IEA GO:0034713 type I transforming growth factor beta receptor binding ISS GO:0046332 SMAD binding IPI GO:0048185 activin binding IPI

Protein-protein interaction details for FKBP1A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TGFBR1 Two-hybrid physical 7518616 YY1 Two-hybrid physical 7541038 MTOR Affinity Capture-Western physical 15467718 RPTOR Affinity Capture-Western physical 15467718 TGFBR1 Two-hybrid physical 7791754 MTOR Affinity Capture-Western physical 15268862 RPTOR Affinity Capture-Western physical 15268862 DHFR Biochemical Activity physical 12812497 RYR1 Affinity Capture-Western physical 12704193 TGFBR1 Affinity Capture-Western physical 7518616 FKBP1A Co-crystal Structure physical 10852943 RYR1 Reconstituted Complex physical 11171121 RYR3 Reconstituted Complex physical 11171121 RYR1 Affinity Capture-Western physical 11171121 RYR1 Reconstituted Complex physical 11279144 MTOR Co-crystal Structure physical 8662507 MTOR Two-hybrid physical 15284440 MTOR Reconstituted Complex physical 15796538 ITPR1 Affinity Capture-Western physical 16278292 MTOR Reconstituted Complex physical 7822316 GLMN Reconstituted Complex physical 8955134 GLMN Two-hybrid physical 8955134 ITPR1 Two-hybrid physical 9346894 RYR3 Reconstituted Complex physical 11598113 BMPR1A Two-hybrid physical 9663660 FKBP1A Co-crystal Structure physical 9871618 GLMN Two-hybrid physical 11164950 GLMN Reconstituted Complex physical 11164950 TGFB1 Two-hybrid physical 11960000 ACVR1B Affinity Capture-Western physical 16720724 SMAD7 Affinity Capture-Western physical 16720724 SMAD7 Affinity Capture-Western physical 16720724 ACVR1B PCA physical 15908921