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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SHANK2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0007420 brain development IEA GO:0035556 intracellular signal transduction NAS cellular_component GO:0005575 cellular_component ND GO:0005622 intracellular NAS GO:0005737 cytoplasm IEA GO:0005886 plasma membrane IEA GO:0014069 postsynaptic density IEA GO:0030054 cell junction IEA GO:0030426 growth cone IEA GO:0043025 neuronal cell body IEA GO:0045202 synapse IEA GO:0045211 postsynaptic membrane IEA molecular_function GO:0005515 protein binding IPI GO:0008022 protein C-terminus binding IEA GO:0017124 SH3 domain binding IEA GO:0030160 GKAP/Homer scaffold activity NAS GO:0035255 ionotropic glutamate receptor binding ISS

Protein-protein interaction details for SHANK2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CTTN Two-hybrid physical 9742101 DNM2 Two-hybrid physical 11583995 ARHGEF7 Two-hybrid physical 12626503 ARHGEF7 Reconstituted Complex physical 12626503 ARHGEF7 Affinity Capture-Western physical 12626503 ARHGEF7 Affinity Capture-Western physical 12626503 DLGAP1 Affinity Capture-Western physical 10844022 DLG4 Affinity Capture-Western physical 10844022 DYNLL2 Affinity Capture-Western physical 10844022 DYNLL1 Affinity Capture-Western physical 10844022 DLGAP1 Affinity Capture-Western physical 10844022 MYO5A Affinity Capture-Western physical 10844022 CTTN Affinity Capture-Western physical 9742101 DLGAP1 Affinity Capture-Western physical 10527873 DLG4 Affinity Capture-Western physical 10527873 DLGAP1 Affinity Capture-Western physical 10527873 DLGAP1 Two-hybrid physical 10527873 DLGAP2 Two-hybrid physical 10527873 DLGAP3 Two-hybrid physical 10527873 DLGAP4 Two-hybrid physical 10527873 DNM2 Affinity Capture-Western physical 11583995 DNM2 Reconstituted Complex physical 11583995