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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for KDM1A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS GO:0006355 regulation of transcription, DNA-dependent IEA GO:0006482 protein demethylation IMP GO:0007275 multicellular organismal development IEA GO:0007596 blood coagulation TAS GO:0016568 chromatin modification IEA GO:0016577 histone demethylation IEA GO:0032091 negative regulation of protein binding IMP GO:0033169 histone H3-K9 demethylation IDA GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor IMP GO:0034720 histone H3-K4 demethylation IDA GO:0043066 negative regulation of apoptosis IMP GO:0043392 negative regulation of DNA binding IC GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity IDA GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity IMP GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator IMP GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity IDA GO:0055001 muscle cell development ISS GO:0055114 oxidation-reduction process IDA cellular_component GO:0000790 nuclear chromatin IDA GO:0000790 nuclear chromatin ISS GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS molecular_function GO:0002039 p53 binding IPI GO:0003682 chromatin binding IDA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IDA GO:0016491 oxidoreductase activity IDA GO:0016491 oxidoreductase activity IEA GO:0019899 enzyme binding IPI GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity IMP GO:0032451 demethylase activity IMP GO:0032452 histone demethylase activity IDA GO:0032453 histone demethylase activity (H3-K4 specific) IDA GO:0032454 histone demethylase activity (H3-K9 specific) IDA GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific) IDA GO:0044212 transcription regulatory region DNA binding ISS GO:0050660 flavin adenine dinucleotide binding IDA GO:0050660 flavin adenine dinucleotide binding IEA GO:0050681 androgen receptor binding IDA GO:0051577 MyoD binding IDA

Protein-protein interaction details for KDM1A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HDAC1 Co-purification physical 12032298 HMG20B Co-purification physical 12032298 HMG20B Affinity Capture-Western physical 12032298 RCOR1 Co-purification physical 12032298 HDAC2 Co-purification physical 12032298 PHF21A Co-purification physical 12032298 HMG20B Affinity Capture-Western physical 12032298 PHF21A Reconstituted Complex physical 15325272 HDAC2 Affinity Capture-MS physical 12493763 ZNF217 Affinity Capture-MS physical 12493763 ZMYM3 Affinity Capture-MS physical 12493763 ZMYM2 Affinity Capture-MS physical 12493763 KIAA0182 Affinity Capture-MS physical 12493763 GTF2I Affinity Capture-MS physical 12493763 KDM1A Affinity Capture-MS physical 12493763 PHF21A Affinity Capture-MS physical 12493763 HMG20B Affinity Capture-MS physical 12493763 HDAC1 Affinity Capture-MS physical 12493763 HDAC2 Affinity Capture-MS physical 12493763 GTF2I Affinity Capture-Western physical 12493763 GTF2I Affinity Capture-Western physical 12493763 HDAC2 Affinity Capture-Western physical 12493763 RCOR1 Affinity Capture-MS physical 11171972 HDAC1 Affinity Capture-Western physical 11171972 HDAC1 Affinity Capture-Western physical 11171972 RCOR1 Affinity Capture-Western physical 11171972 SIN3A Affinity Capture-Western physical 11171972 HDAC2 Affinity Capture-MS physical 9804427 IMMT Two-hybrid physical 16169070 CCDC90B Two-hybrid physical 16169070 UNC119 Two-hybrid physical 16169070 SETDB1 Two-hybrid physical 16169070 ATP5J2 Two-hybrid physical 16169070 GDF9 Two-hybrid physical 16169070 ASCC2 Two-hybrid physical 16169070 WHSC1 Affinity Capture-Western physical 18156491 ZMYM2 Affinity Capture-MS physical 18806873 RCOR1 Reconstituted Complex physical 18806873 POLR2B Affinity Capture-MS physical 17643375 PRDM1 Affinity Capture-Western physical 19124609 PRDM1 Affinity Capture-Western physical 19124609 PRDM1 Reconstituted Complex physical 19124609 ZNF217 Affinity Capture-MS physical 19242095 HIST1H3A Biochemical Activity physical 16956976 RCOR1 Reconstituted Complex physical 16956976 RCOR1 Co-crystal Structure physical 16885027 ZNF217 Affinity Capture-Western physical 18625718 SUMO2 Affinity Capture-MS physical 19394292 SUMO2 Reconstituted Complex physical 19394292 TP73 Affinity Capture-Western physical 18573881 TP53 Affinity Capture-Western physical 18573881 TP53 Reconstituted Complex physical 18573881 ESCO2 Affinity Capture-Western physical 18501190 HIST1H3A Protein-peptide physical 16223729 RREB1 Affinity Capture-MS physical 16140033 ZMYM2 Affinity Capture-MS physical 16140033 ZNF217 Affinity Capture-MS physical 16140033 PHF21A Affinity Capture-MS physical 16140033 HSPA1A Affinity Capture-MS physical 16140033 RCOR1 Affinity Capture-MS physical 16140033 HDAC1 Affinity Capture-MS physical 16140033 CTBP1 Affinity Capture-MS physical 16140033 HMG20A Affinity Capture-MS physical 16140033 HMG20B Affinity Capture-MS physical 16140033 HIST1H3A Biochemical Activity physical 16140033 RCOR1 Reconstituted Complex physical 16140033 ZMYM3 Affinity Capture-MS physical 16079794 ZMYM2 Affinity Capture-MS physical 16079794 ZNF516 Affinity Capture-MS physical 16079794 KIAA0182 Affinity Capture-MS physical 16079794 ZNF217 Affinity Capture-MS physical 16079794 PHF21A Affinity Capture-MS physical 16079794 RCOR1 Affinity Capture-MS physical 16079794 HDAC1 Affinity Capture-MS physical 16079794 HDAC2 Affinity Capture-MS physical 16079794 CTBP1 Affinity Capture-MS physical 16079794 HMG20B Affinity Capture-MS physical 16079794 HIST1H3A Biochemical Activity physical 16079794 RCOR1 Co-fractionation physical 16079794 NR2E1 Affinity Capture-MS physical 18391013 NR2E1 Affinity Capture-Western physical 18391013 NR2E1 Reconstituted Complex physical 18391013 RB1 Affinity Capture-Western physical 18216119 RB1 Affinity Capture-Western physical 18216119 HDAC1 Affinity Capture-MS physical 11102443 HDAC1 Affinity Capture-Western physical 11102443 RCOR1 Affinity Capture-Western physical 11102443 HDAC1 Affinity Capture-Western physical 11102443 HDAC2 Affinity Capture-Western physical 11102443 RCOR1 Affinity Capture-Western physical 11102443 HDAC2 Affinity Capture-Western physical 11102443 CTBP1 Affinity Capture-Western physical 17967884 CTBP1 Reconstituted Complex physical 17967884 ZNF217 Affinity Capture-Western physical 17967884 TP53 Affinity Capture-Western physical 17805299 TP53 Reconstituted Complex physical 17805299 TP53 Reconstituted Complex physical 17805299 TP53 Affinity Capture-Western physical 17805299 TP53 Biochemical Activity physical 17805299 HIST2H3C Co-crystal Structure physical 17687328 HDAC1 Affinity Capture-Western physical 17634443 MBD2 Affinity Capture-Western physical 17634443 HDAC1 Affinity Capture-Western physical 17634443 MBD2 Affinity Capture-Western physical 17634443 ESR1 Affinity Capture-Western physical 17289570 ESR1 Affinity Capture-Western physical 17289570 EP300 Affinity Capture-Western physical 17289570 PELP1 Affinity Capture-Western physical 20448663 PELP1 Reconstituted Complex physical 20448663 PELP1 Co-localization physical 20448663 PELP1 Co-localization physical 20448663 E2F1 Biochemical Activity physical 20603083 HDAC1 Affinity Capture-MS physical 20585571 ESCO1 Affinity Capture-Western physical 20331966 SNAI1 Reconstituted Complex physical 20562920 SNAI1 Affinity Capture-Western physical 20562920 HIST1H3A Biochemical Activity physical 20228790 RCOR1 Affinity Capture-Western physical 20164337 HDAC2 Affinity Capture-Western physical 20164337 CTBP1 Affinity Capture-Western physical 20547759 BCL3 Affinity Capture-Western physical 20547759 HDAC1 Affinity Capture-Western physical 20856864 HDAC1 Affinity Capture-Western physical 20856864 MEF2D Affinity Capture-Western physical 20833138 GFI1B Affinity Capture-Western physical 17707228 GFI1 Affinity Capture-Western physical 17707228 RCOR1 Reconstituted Complex physical 21142040 PPP1R12A Affinity Capture-MS physical 21115810 PPP1R12A Affinity Capture-Western physical 21115810 PPP1R12A Reconstituted Complex physical 21115810 PPP1R12A Biochemical Activity physical 21115810 MTA2 Affinity Capture-MS physical 19703393 CHD3 Affinity Capture-Western physical 19703393 HDAC1 Affinity Capture-Western physical 19703393 HDAC2 Affinity Capture-Western physical 19703393 MTA1 Affinity Capture-Western physical 19703393 MTA2 Affinity Capture-Western physical 19703393 MTA3 Affinity Capture-Western physical 19703393 MBD3 Affinity Capture-Western physical 19703393 MTA1 Reconstituted Complex physical 19703393 MTA2 Reconstituted Complex physical 19703393 MTA3 Reconstituted Complex physical 19703393 SNAI1 Affinity Capture-MS physical 20389281 SNAI1 Affinity Capture-Western physical 20389281 SNAI1 Affinity Capture-Western physical 20389281 RCOR1 Affinity Capture-Western physical 20389281 SNAI1 Co-localization physical 20389281 TAL1 Affinity Capture-MS physical 19497860 TAL1 Affinity Capture-Western physical 19497860 TAL1 Affinity Capture-Western physical 19497860 TAL1 Reconstituted Complex physical 19497860 CDC5L Two-hybrid physical 17043677 EXOC1 Two-hybrid physical 17043677 ZBP1 Affinity Capture-MS physical 21903422 UBC Affinity Capture-MS physical 21987572